But he now must weigh up how much he changes a winning side, following the fantastic 4-1 victory at Fulham.
As it has been for some time, the decision on whether to play a back four or back five remains a big one.
Bournemouth play with a four and due to decisions elsewhere in the team, O'Neil may stick with a four himself.
Jose Sa should keep his place in the net, while I would be surprised if Craig Dawson was not recalled at the heart of defence.
It then begs the question of whether to play three midfielders or play an extra attacking player, like they did at Fulham.
Liam Keen's predicted XI
Liam Keen's predicted XI
I could see either situation happening, but the decision on who to drop from midfield is a tough one and I predict all three of Andre, Joao Gomes and Mario Lemina will start.
That would mean playing Matheus Cunha on the left, while on the right I predict Jean-Ricner Bellegarde will play, with Hwang Hee-chan probably not quite ready to start.