Manchester United duo Kobbie Mainoo and Lisandro Martinez won't be available for the Premier League clash against Arsenal on the road on Wednesday night.
Mainoo made his first appearance since recovering from a calf injury earlier today. He played the full 90 minutes, but he will be suspended for the visit of the Emirates Stadium.
The United graduate picked up his fifth booking of the top-flight campaign against the Toffees. As a result, he will serve a one-game suspension against Mikel Arteta's side.
Similarly, Martinez was handed his fifth yellow card of the season, just a couple of minutes after Mainoo's booking. The Argentine won't be available for the London trip.
Mainoo's absence should pave the way for Manuel Ugarte to partner Casemiro in midfield. Martinez's suspension means Luke Shaw will get the nod as the left centre-back.
Shaw has already trained under manager Ruben Amorim in the position. He has made a handful of appearances in the same role and should be in line to start against the Gunners.