Liverpool have scored 48 Premier League goals at St. James' Park – their joint-most in the competition alongside the home of West Ham United.
The 15 evening kick-offs (7pm or later) between the clubs in the Premier League have produced 51 goals (3.4 per game).
Liverpool have won 16 of their last 18 midweek Premier League fixtures.
If Mohamed Salah scores, he will equal his best run of netting in seven successive league games for the club, set between August and October 2021.
The Egyptian has been involved in 14 Premier League goals versus the Magpies (eight goals, six assists).
Trent Alexander-Arnold only has more Premier League goal involvements against Arsenal (seven) and West Ham (six) than he does versus Newcastle (five – one goal, four assists).
Arne Slot's side have taken 16 points from a possible 18 away from home in the league this season.
They have won each of the 15 games this term in which they have scored the first goal.