Chelsea travel to the South Coast on Wednesday night as they aim to get their fourth win in a row.
The Blues come off the back of an impressive 3-0 win against Champions League side Aston Villa in the Premier League in a game where goals came from Nicolas Jackson, Cole Palmer and Enzo Fernandez who has two in two games.
Enzo Maresca‘s side now sit third in the league behind second-placed Arsenal by just alphabetical order heading into the 14th game of the season.
Chelsea could overtake Arsenal who faces a tough game against Ruben Amorim’s Manchester United on Wednesday night at the Emirates.
The Blues have a relatively fit squad, however they could miss two players on Wednesday. Defender Wesley Fofana has been ruled out with a hamstring injury that he suffered against Villa.
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Club captain Reece James also remains out with an aggravated hamstring issue that he has had problems with for the past few seasons.
Click here to see our predicted XI for Maresca on Wednesday night as the Blues face bottom of the league side Southampton who come off a 1-1 draw to Brighton.
Chelsea backed heavily to beat Southampton
Unsurprisingly, title contenders Chelsea are backed to comfortably beat Russell Martin’s side who are currently six points away from safety.
According to Oddschecker, Chelsea are 1/3 favourites to win on Wednesday which gives them a 75% chance to win against the Saints.
Southampton are backed at odds of 9/1 giving them a 10% chance to win and a draw is backed at 21/4 (16%).
We predict a 4-1 win for the Blues as they should come through the game comfortably despite being at St Mary’s Stadium.
Where to watch the Blues’ trip to Southampton
The game kicks off at 7.30 pm on Wednesday 4 December at St Mary’s Stadium and will be broadcast live on Prime Video for Amazon Prime customers.
Highlights will be broadcast on BBC One at 10.40 pm on Wednesday night for Match of the Day.