Set to welcome Manchester City to Turin on Wednesday evening, draw specialists Juventus will be seeking a first win in four Champions League matches.
Like their Premier League counterparts, the Serie A giants have recently seen their treatment room overflowing with injured players, and many will still be missing in midweek.
Summer signings Nico Gonzalez, Juan Cabal and Douglas Luiz are all unavailable, while USA midfielder Weston McKennie is a major doubt; Brazilian centre-back Bremer - Juve's defensive rock - has been ruled out for the rest of season by an ACL tear.
In better news for Bianconeri boss Thiago Motta, his main marksman Dusan Vlahovic returned to the starting XI on Saturday, having missed almost a month with the thigh injury he picked up while representing Serbia.
With his deputy - Poland forward Arkadiusz Milik - still sidelined following knee surgery, Vlahovic will spearhead Juve's attack; however, his last league goal from open play at the Allianz Stadium came way back in February - some 13 games ago.
Support for the hosts' lone striker is usually provided by Teun Koopmeiners, with Francisco Conceicao - who has completed 18 dribbles in four Champions League games this season - favourite to occupy the right flank.
Motta must choose between Kenan Yildiz and a recently revived Timothy Weah to start on the left, and Juve's highly-rated head coach will also weigh up his options at full-back.
Following a brief layoff, Nicolo Savona returned to action at the weekend, while former Man City defender Danilo and Italy international Andrea Cambiaso can play on either side - albeit the latter has suffered an ankle sprain and may miss out.
Meanwhile, Mattia Perin has been preferred to Michele Di Gregorio in goal over the past couple of weeks, but it remains to be seen who features between the posts on Wednesday.
Juventus possible starting lineup: Perin; Savona, Kalulu, Gatti, Danilo; Locatelli, Thuram; Conceicao, Koopmeiners, Weah; Vlahovic
> Click here to see how Manchester City could line up for Wednesday's Champions League contest
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