The Bills have the No. 2 scoring offense in the NFL (30.5) just behind Detroit (32.1).
Detroit has their own MVP candidate in Jared Goff, who ranks second among quarterbacks in completion percentage (72.4) and passer rating (109.1) and is fifth in touchdown passes (25).
In a contest featuring the top two scoring offenses in the league, both defenses will be pressed to make plays, and that could ultimately be the difference. The Lions have the No. 2 scoring defense (18.0) in the NFL heading into the matchup. They rank 10th in total defense, 23rd against the pass and fifth against the run. Buffalo's defense comes in at eighth in scoring (20.6), and they're 14th in total defense, ninth against the pass and 19th against the run.