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49ers rule out star player, list another as questionable

The San Francisco 49ers injury issues got a little more clarity on Wednesday, as the team officially ruled out All-Pro left tackle Trent Williams to face the L.A. Rams on Thursday. And All-Pro edge rusher Nick Bosa is questionable after going through a limited walk-through on Wednesday.

This is a must-win game for both teams — but mostly for the 49ers — so every name that’s in or out will be crucial.

Williams has missed the last three games with an ankle injury. The 36-year-old with a gold jacket waiting for him in Canton has not played 16 in a season since 2013.

Bosa has also missed the last three games, but it is not clear yet if he will also miss a fourth in a row. The 2022 Defensive Player of the Year has 7 sacks in 10 games this year. But in that time, former Rams edge rusher Leonard Floyd has stepped up in his place:

Floyd has 4 sacks in the three games that Bosa has missed and he has a team-leading 8.5 sacks on the season. He’s on track to set a new career-high for sacks if he can add 2.5 more to his tally in the final four games.

The 49ers have been starting Jaylon Moore, a 2021 fifth round out of Western Michigan, at tackle in Williams’ absence.

San Francisco beat the Bears last week 38-13, but the 49ers haven’t won back-to-back games in consecutive weeks all season long. The 49ers did beat the Cowboys and Bucs in back-to-back games, but they had a bye in between those.

The Rams are not yet sure if Cobie Durant will miss this week.

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