**2) Limit Kittle and Jennings' impact**
Tight end George Kittle was inactive for the first matchup in Week 3. Now healthy, he's coming off one of his best performances of the season against the Bears, posting six catches for 151 yards.
Wide receiver Jauan Jennings was active in Week 3, however, and had a massive game – 11 catches for 175 yards and 3 touchdowns. Against the Bears, he had seven catches for 90 yards and two touchdowns.
Keeping the 49ers' offense in check starts with mitigating the impact those two have on the game, as quarterback Brody Purdy has consistently fed them targets since top receiver Brandon Aiyuk suffered a season-ending knee injury in Week 7.