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NFL Week 15 picks: Big implications behind Rams-49ers and Bills-Lions matchups

Denver Broncos quarterback Bo Nix (10) sets to throw against the Browns.

Rookie quarterback Bo Nix (10) has led the Broncos to eight wins and put them firmly in playoff contention.

(David Zalubowski / Associated Press)

Sunday, 1:25 p.m. TV: NFL Ticket

Line: Broncos by 3½. O/U: 44½.

Denver’s defense is legit, and Bo Nix is doing surprisingly well in that offense. The Colts will try to run it, and they should stay in the game for a while. But Nix makes more plays than Anthony Richardson.

Pick: Broncos 24, Colts 20

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