Marcus Rashford has not travelled with the Manchester United squad for their game against Tottenham, talkSPORT understands.
The Red Devils forward was dropped for the 2-1 Manchester derby win over Manchester City on Sunday, as was Alejandro Garnacho.
Rashford hasn't travelled for Spurs and he will not feature in the cup clash
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Rashford hasn't travelled for Spurs and he will not feature in the cup clashCredit: Getty
And he has not gone down to London with the rest of his team on Wednesday for the Carabao Cup quarter-final tie on Thursday, live on talkSPORT.
Garnacho, meanwhile, has travelled down for the game.
Rashford was absent from training on Monday, with reports claiming he was sent home due to a sickness bug.
The 27-year-old visited his old school on Tuesday to hand out presents to students.
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It was there that he revealed he was ready for a 'new challenge' beyond Old Trafford.
Asked about Rashford on Wednesday, manager Ruben Amorim said: “This is in the future.
"My focus is to have all the players in the best that they can be to prepare for each game.
“We are talking about if there is no if in this kind of club. It's just talk to them and let's focus on the game.”
Pressed on Rashford's view that he needs a new challenge, he stated: "I think it’s right.
"We have here a new challenge, it’s a tough one, for me it’s the biggest challenge in football because we are in a difficult situation and I already said this is one of the biggest clubs in the world.
Garnacho is expected to have some involvement in the cup tie, however
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Garnacho is expected to have some involvement in the cup tie, howeverCredit: Getty
"This is a really new challenge and the biggest one. I really hope all my players are ready for this new challenge."
Amorim said at the time that he had not yet spoken to Rashford.
"No, not yet," he said. "It was yesterday, I gave the day off to the lads, so he’s our player and he’s ready for the next game.
"I spoke with a lot of players individually and during training, what I want is to take the best stuff of Marcus Rashford as the player so I don’t talk about the future.
"I just talk about the present, I want the best of each one of them and that is the key point for me, I just want to win and to help the team be better."
Rashford, now 27, has been at the club since the age of seven.
Rashford won the FA Cup with Man United at the end of last season
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Rashford won the FA Cup with Man United at the end of last seasonCredit: Getty
He has bagged 138 goals in 426 first team appearances, winning the FA Cup twice, the League Cup twice and the Europa League in that time.
He was also crowned Man United's Player of the Year in 2020 and 2023.
However the former England international's form has dipped of late, going from scoring 30 in all competitions in 2022/23 to netting eight last season.
Speaking to journalist Henry Winter, Rashford said: “For me, personally, I think I'm ready for a new challenge and the next steps.
"When I leave it's going to be ‘no hard feelings’. You’re not going to have any negative comments from me about Manchester United. That’s me as a person.
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"If I know that a situation is already bad I'm not going to make it worse. I've seen how other players have left in the past and I don't want to be that person.
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"When I leave I'll make a statement and it will be from me. 100 per cent."