The duo though have now both recovered from their muscular issues, have trained with the squad and are now back and available for Ange to select with United our latest opponents in the top flight.
"Madders is a little bit ahead of schedule (in his recovery)," Ange explained as he spoke to us on Friday morning. "He’s feeling really good. He’s had a good week of training. We were thinking maybe (it'll be) next week for him, but he’s trained really well all week, and he’s had the least amount of time out, so he’s looking in a good place.
"Of the longer-term (injuries), Destiny is back in team training as well, which is good. He’s ticked all the boxes in terms of getting through his rehab and conditioning, so he’s part of the squad."
Elsewhere, Brennan Johnson and Timo Werner have both returned to training this week and are edging ever closer to returning to the field. Meanwhile, there is positive news on Wilson Odobert as he has also returned to the grass but caution will be taken with his reintegration after a lengthy spell on the sidelines.
Cristian Romero, Micky van de Ven, Radu Dragusin, Dominic Solanke and Richarlison all remain sidelined for this weekend's game.