With both teams already through to the knockout stage, City underlined their status as title favourites by becoming the only team to finish the group phase with three wins, showing flashes of their brilliant selves.
Guardiola's side, will meet Al-Hilal - coached now by Simone Inzaghi, who steered Inter Milan into the last Uefa Champions League final - in the last 16. City finished three points clear of Juventus, who will face Real Madrid.
Vinicius Jr scored one and set up another as Madrid secured a 3-0 victory over RB Salzburg on Thursday to seal top spot in Group H.
The Spaniards finished with seven points, two clear of Saudi Arabia's Al-Hilal, who defeated Pachuca 2-0 in the day’s other group fixture. Austria's Salzburg, with four points, and Mexican side Pachuca, who failed to register a point, were eliminated.
Real face Juve at the Hard Rock Stadium in Miami on Tuesday, while Hilal met City in Orlando on Monday.