By ASSOCIATED PRESS
Published: 21:32 BST, 7 September 2025 | Updated: 21:32 BST, 7 September 2025
NEW ORLEANS (AP) - Kyler Murray threw two touchdown passes and the Arizona Cardinals narrowly held on for a 20-13 victory over penalty-prone New Orleans on Sunday in the Saints' first game under rookie coach Kellen Moore.
Murray passed for 163 yards, hitting Marvin Harrison Jr. five times for 71 yards and a TD. Murray also rushed for 38 yards and his other TD toss came on a 4-yard shovel pass to running back James Conner.
Saints star running back Alvin Kamara scored on an 18-yard, tackle-slipping touchdown run around the right end. Spencer Rattler passed for 214 yards without a turnover and nearly rallied the Saints into a tie during the final five minutes.
Rattler, a second year pro who has now lost all seven of his NFL starts, drove the Saints for Blake Grupe's short field goal to pull New Orleans within a touchdown with 2:42 left.
After Alontae Taylor's third-down sack on a cornerback blitz forced Arizona to punt from inside the 20, the Saints began a potential tying drive on their 42 with just less than two minutes left.
Without any timeouts, Rattler scrambled for 9 yards and completed five quick passes to move the Saints to the Arizona 18. After a spike to stop the clock with 13 seconds left, Rattler took three shots at the end zone. All fell incomplete, but the second throw nearly connected with leaping tight end Juwan Johnson, who lost control of the ball as he came down hard in the end zone.
Arizona Cardinals quarterback Kyler Murray (1) throws against New Orleans Saints defensive ends Cameron Jordan (94) and Carl Granderson during the first half of an NFL football game Sunday, Sept. 7, 2025, in New Orleans. (AP Photo/Butch Dill)
The Saints, who saw their streak of six season-opening victories snapped, took a brief first-half lead on Kamara's scoring run in the second quarter.
Soon after, Murray's [45-yard pass to Harrison](https://x.com/AZCardinals/status/1964747169262350340) set up Arizona's first TD on Harrison's 1-yard catch that put Arizona in front for good.
New Orleans responded with Grupe's tying 36-yard field goal before Conner's TD made it 17-10 with 28 seconds left in the half.
Chad Ryland's 50-yard field goal made it 20-10 in the third quarter, but Ryland's 46-yard attempt to further widen Arizona's lead was blocked by defensive tackle Bryan Bresee, setting the stage for late-game drama.
Saints defensive end Cameron Jordan, now in his 15th season, was expected to play more of a reserve role this season but started because Chase Young was out with a calf injury. Jordan had 1 1/2 sacks, pushing his career total to 123, tied for 20th in the NFL all-time with Robert Mathis.
The Saints were penalized 13 times for 89 yards, with many infractions coming on improper alignments, shifts or motion by the offense. The Cardinals were flagged nine times for 54 yards.
Cardinals linebacker Cody Simon and safety Joey Blount both were shaken up on kickoff coverage late in the first half. Simon was able to walk back to the sideline while Blount walked straight to the locker room with medical staff.
Saints right tackle Taliese Fuaga went to the sideline with a knee injury in the second half. He stayed in the bench area but did not play again. Top receiver Chris Olave removed his helmet and went to the sideline after being leveled on a receiver screen. The Saints said he had a chest injury, but he returned to the game.
Arizona hosts Carolina on Sunday, while New Orleans hosts San Francisco.
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Arizona Cardinals safety Jalen Thompson (34) and Cardinals safety Budda Baker (3) break up a pass intended for New Orleans Saints tight end Juwan Johnson (83) during the second half of an NFL football game Sunday, Sept. 7, 2025, in New Orleans. (AP Photo/Butch Dill)
New Orleans Saints running back Alvin Kamara (41) gets past Arizona Cardinals safety Dadrion Taylor-Demerson for a touchdown during the first half of an NFL football game Sunday, Sept. 7, 2025, in New Orleans. (AP Photo/Gerald Herbert )
Arizona Cardinals wide receiver Marvin Harrison Jr., left, makes a touchdown catch against New Orleans Saints cornerback Kool-Aid McKinstry during the first half of an NFL football game Sunday, Sept. 7, 2025, in New Orleans. (AP Photo/Butch Dill)
New Orleans Saints quarterback Spencer Rattler throws against the Arizona Cardinals during the first half of an NFL football game Sunday, Sept. 7, 2025, in New Orleans. (AP Photo/Butch Dill)