NOW PLAYING video Can't-Miss Play: 46-yard TD! Henry's sideline sprint stymies Bills' comeback hopes Baltimore Ravens running back Derrick Henry scores his second touchdown of the night after a 46-yard rush.
NOW PLAYING video Can't-Miss Play: Lamar Jackson roams the globe on 19-yard rush that wows Collinsworth Baltimore Ravens quarterback Lamar Jackson breaks away for 19 yards.
NOW PLAYING video Can't-Miss Play: James Cook's 51-yard catch and run comes after Allen's pre-snap audible Buffalo Bills running back James Cook takes it for 51 yards following an audible from quarterback Josh Allen.
video Can't-Miss Play: One-handed TD catch by Hopkins! Nuk's first Ravens snag is 33-yard score Baltimore Ravens wide receiver DeAndre Hopkins reels in a one-handed 33-yard touchdown from quarterback Lamar Jackson.
video Can't-Miss Play: 49-yard run! Derrick Henry gashes Bills in first half of 'SNF' Baltimore Ravens running back Derrick Henry sneaks through the Buffalo Bills defense for 49 yards.
video Can't-Miss Play: 30-yard TD! Derrick Henry stiff-arms Cole Bishop into ground on score Baltimore Ravens running back Derrick Henry rushes for 30 yards to put the Ravens up 10-7 against the Buffalo Bills.
video Can't-Miss Play: Landman for the win! Rams' new LB seals the deal vs. Texans Los Angeles Rams linebacker Nate Landman forces a fumble that is subsequently recovered by defensive end Braden Fiske against the Houston Texans during Week 1 of the 2025 NFL season.
video Can't-Miss Play: Bosa's strip-sack of Darnold seals 49ers' Week 1 win vs. Seahawks San Francisco 49ers' defensive lineman Nick Bosa forces and recovers a game-winning fumble from Seattle Seahawks' quarterback Sam Darnold.
video Can't-Miss Play: Darnold's 40-yard dime to Smith-Njigba comes in crunch time vs. 49ers Seattle Seahawks' quarterback Sam Darnold answers a go-ahead score by the San Francisco 49ers' with a 40-yard strike to wide receiver Jaxon Smith-Njigba to set the Seahawks' up inside 49ers' territory late in the fourth quarter.
video Can't-Miss Play: Catch of the year? Isaac TeSlaa channels OBJ on one-handed TD vs. Packers Detroit Lions wide receiver Isaac TeSlaa closes out the Week 1 game against the Green Bay Packers with a one-handed touchdown grab.
video Can't-Miss Play: Go-ahead TD! Purdy's improbable scoring strike hits Tonges vs. Seahawks San Francisco 49ers' quarterback Brock Purdy buys time and finds tight end Jake Tonges for a go-ahead touchdown late in the fourth quarter vs. the Seattle Seahawks.
video Can't-Miss Play: Micah Parsons' first sack as a Packer comes in fourth quarter vs. Goff The Lambeau Field crowd erupts as defensive lineman Micah Parsons records his first sack as a member of the Green Bay Packers in the season opening game against the Detroit Lions.
video Can't-Miss Play: 45-yard launch! Purdy and Pearsall burn Seahawks on double-move concept San Francisco 49ers' quarterback Brock Purdy goes deep to wide receiver Ricky Pearsall for 45 yards on a potential game-winning driver vs. the Seattle Seahawks.
video Can't-Miss Play: Cobie Durant steals football away from Higgins for epic INT Los Angeles Rams cornerback Cobie Durant intercepts the pass from Houston Texans quarterback C.J. Stroud intended for wide receiver Jayden Higgins during Week 1 of the 2025 NFL season.
video Can't-Miss Play: Seahawks block Moody's field goal to preserve 10-7 lead Seattle Seahawks' safety Julian Love blocks San Francisco 49ers' kicker Jake Moody's 36-yard field goal attempt and the Seahawks recover to retain their 10-7 lead.
video Can't-Miss Play: 71-yard kick return! Chimere Dike burns Broncos with his speed Tennessee Titans wide receiver Chimere Dike burns Denver Broncos with his speed.
video Can't-Miss Play: Roger McCreary overpowers Sutton at catch point for epic INT Tennessee Titans cornerback Roger McCreary overpowers Denver Broncos wide receiver Courtland Sutton at catch point for epic interception.
video Can't-Miss Play: One-handed INT! Jaycee Horn goes WAY upstairs to pick off Lawrence's launch Carolina Panthers' defensive back Jaycee Horn robs Jacksonville Jaguars' quarterback Trevor Lawrence of a long completion with an outstanding one-handed interception.
video Can't-Miss Play: Mayfield's 25-yard TD pass to Egbuka puts Bucs ahead of Falcons with 0:59 left Tampa Bay Buccaneers quarterback Baker Mayfield throws a 25-yard touchdown pass to wide receiver Emeka Egbuka to put Buccaneers ahead of the Atlanta Falcons with 0:59 left.
video Can't-Miss Play: Jacory Croskey-Merritt hits turbo button on 42-yard burst! Washington Commanders running back Jacory Croskey-Merritt rushes for 42 yards against the New York Giants during Week 1 of the 2025 NFL season.
video Can't-Miss Play: Ramsey's hit-stick PBU vs. Garrett Wilson seals Steelers' Week 1 win Pittsburgh Steelers cornerback Jalen Ramsey's hit-stick PBU vs. New York Jets wide receiver Garrett Wilson seals Steelers' Week 1 win.
video Can't-Miss Play: 60-yard FG for the lead! Boswell has ice in his veins vs. Jets Pittsburgh Steelers kicker Chris Boswell has ice in his veins vs. the New York Jets as he kicks his career long 60-yard field goal.
video Can't-Miss Play: How did this happen?! DK Metcalf snags catch after bizarre ricochet Pittsburgh Steelers wide receiver DK Metcalf snags catch after bizarre ricochet for 11 yards.
video Can't-Miss Play: Deebo Samuel's epic pylon reach caps his first TD as a Commander Washington Commanders wide receiver Deebo Samuel Sr. rushes for 19 yards and a touchdown against the New York Giants in Week 1 of the 2025 NFL season.
video Can't-Miss Play: 36-yard dime! Geno Smith's deep ball dots Dont'e Thornton Jr. vs. Pats Las Vegas Raiders quarterback Geno Smith completes a 36-yard pass to wide receiver Dont'e Thornton.