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49ers’ star George Kittle (hamstring) expected to miss ‘multiple weeks’

The San Francisco 49ers’ offense continues to be damaged by injuries to start 2025. Star tight end George Kittle, who was having a great first half, went down with a hamstring injury.

Before that point, he had tallied 25 yards on four receptions and seemed to be a comfortable safety valve for QB Brock Purdy.

Kittle was unable to return for the remainder of the action and will reportedly miss additional weeks.

Head coach Kyle Shanahan told reporters in San Francisco that Kittle is expected to “be out a few weeks.”

It was a big-time catch. Earlier in that drive he had his first NFL catch and it was followed the next play by his second. I want to say it was three plays later by the game winner. So, I think Brock just ended up getting confidence in him very quickly as the drive went.”

When asked if the 31-year-old may be placed on Injured Reserve, Shanahan said, “When they tell me a few weeks, it’s always a possibility.”

“In order to do that, it’s got to be a four-week injury,” he continued. “So, I don’t think we’ve decided on that yet.”

Undrafted in 2022, Jake Tonges stepped up for Kittle in Seattle, securing the first catch of his career.

And his first touchdown reception ended up being the game-winner, a promising start for the young player.

Jake Tonges had never caught a pass in the NFL before today.

He has three today. Including this one 🙌 pic.twitter.com/g1xMS2UXub

— NFL (@NFL) September 7, 2025

It was a big-time catch,” Shanahan said of Tonges on Monday. “Earlier in that drive he had his first NFL catch and it was followed the next play by his second.

“I want to say it was three plays later by the game winner,” he continued. “So, I think Brock just ended up getting confidence in him very quickly as the drive went on.”

Tonges will have more opportunity in Kittle’s absence, while the wide receiver room adds a familiar face in Kendrick Bourne, who reportedly agreed to a one-year deal with San Francisco.

More San Francisco 49ers Coverage on Sactown Sports

The San Francisco 49ers are adding another target for Brock Purdy, bringing back a familiar face.

Wide receiver Kendrick Bourne is reportedly re-signing with San Francisco on a one-year deal worth up to $5 million, according to ESPN’s Adam Schefter.

Dealing with a depleted WR room headed into Sunday’s season debut in Seattle, head coach Kyle Shanahan was utilizing tight end George Kittle in the pass game.

Read More:

Report: San Francisco 49ers sign returning WR Kendrick Bourne

Upcoming San Francisco 49ers Schedule

Sunday, September 14th – @ New Orleans Saints – 10:00 AM PT

Sunday, September 21st – vs. Arizona Cardinals – 1:25 PM PT

Sunday, September 28th – vs. Jacksonville Jaguars – 1:05 PM PT

Thursday, October 2nd – @ Los Angeles Rams – 5:15 PM PT

Sunday, October 12th – @ Tampa Bay Buccaneers – 10:00 AM PT

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