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Updated Cowboys vs. Giants prediction following Malik Nabers injury news

The NFC East rivalry takes the spotlight on Sunday, September 14, as the New York Giants visit the Dallas Cowboys at AT&T Stadium. Bet365 is rolling out fresh Bet Boost parlays for this divisional matchup, highlighting playmakers such as Dak Prescott, CeeDee Lamb, and Malik Nabers, who received a positive injury update earlier in the week.

New NFL Week 2 odds boosts for Malik Nabers, CeeDee Lamb, and more

Bet365 is featuring a lineup of Bet Boost parlays for Sunday’s NFC East showdown between the Giants and Cowboys. Here’s a breakdown of the featured boosts:

Sunday Service

Legs: Javonte Williams to Score a TD, Malik Nabers to Score a TD, CeeDee Lamb to Score a TD

Odds were +825, boosted to +1000

Money Malik

Legs: Malik Nabers 8+ Receptions, Malik Nabers 100+ Rec Yards, Malik Nabers to Score a TD

Odds were +625, boosted to +750

In a Rush

Legs: Tyrone Tracy Jr. 60+ Rush Yards, Javonte Williams 60+ Rush Yards, Both Teams to Score 20+ Points – Yes

Odds were +850, boosted to +1000

Dak Attack

Legs: Cowboys Money Line, Dak Prescott 300+ Pass Yards, Dak Prescott 2+ Pass TDs

Odds were +475, boosted to +550

CD + GP

Legs: Cowboys Money Line, CeeDee Lamb 80+ Rec Yards, George Pickens 80+ Rec Yards

Odds were +850, boosted to +1000

Dallas Domination

Legs: Cowboys Money Line, First Score Method: Cowboys Touchdown, Cowboys First to 30 Points

Odds were +440, boosted to +500

These Bet Boosts highlight star power on both sides, with stars like Malik Nabers, Dak Prescott and CeeDee Lamb headlining the action. For bettors, they add extra value to what’s already one of Week 2’s marquee divisional games.

Game details: Cowboys vs. Giants NFL Week 2

Date: Sunday, September 14, 2025

Time: 1:00 PM ET

Venue: AT&T Stadium

NFL stats, rosters and injury reports

Odds

Spread: Cowboys favored at -5.5

Total (Over/Under): 44.5

Moneyline Odds: Giants +205, Cowboys -225

Note: The NFL odds in this article are correct at time of publication and subject to change.

Promos

BetMGM: $150 in bonus bets via bonus code SILIVE150 (NJ eligible), or a $1,500 first bet offer with BetMGM bonus code CUSE150 nationwide.

Bet365: $200 in bonus bets with bonus code SILIVE in NJ, or SYRACUSE in all other legal Bet365 states.

Dimers’ prediction and best bet

Dimers analysts simulated the Giants vs. Cowboys matchup 10,000 times and project Dallas to come out on top in a competitive battle, 24-20. The model gives the Cowboys a 64% chance of victory, while the Giants sit at 36%. The spread has Dallas favored at -5.5, but the simulations highlight value on New York keeping it close. With a 57.7% probability of covering, Giants +5.5 stands out as the strongest play.

Best bet: Giants +5.5 (-113)

Final thoughts: Giants vs. Cowboys Week 2

This NFC East rivalry is set to deliver its usual intensity, with Dak Prescott and CeeDee Lamb leading the Cowboys against a Giants team eager to make a statement behind rookie Malik Nabers. Dimers’ model leans toward Dallas winning outright, but the numbers suggest New York can stay within the spread. Expect a physical, low-scoring divisional clash where every possession matters.

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