Sunday's crucial Week 5 matchup between the Patriots (2-2) and the undefeated Bills (4-0) will take place at Highmark Stadium in Orchard Park.
Buffalo's season could not have begun more smoothly. The frightening thing is that the Bills have already won four in a row and they haven't even reached their peak yet. As the AFC’s lone undefeated team, they’ve built themselves a two-game cushion atop the division and now have a wonderful chance to strengthen their grip even more with another victory.
However, across the field is a New England squad that has a 2-2 start to the 2025 season and doesn't resemble the cellar-dwellers of the previous two seasons.
The Patriots are carrying swagger and bite thanks to an improved squad, Mike Vrabel's aggressive leadership, and a steadying presence at quarterback in Drake Maye, who has been their best play since Tom Brady left town in 2019.
Here is everything you need to know in order to listen to the Bills vs. Patriots on the radio.
Bills vs. Patriots radio station
National radio channels:SiriusXM channel 225 (home), 226 (away)
Bills radio channel: WGR 550 AM (SportsRadio 550)
**Patriots radio channels:**98.5 The Sports Hub
You can listen to the Bills vs. Patriots live on SiriusXM. Coverage will be available on channels 225 (Buffalo Bills) and 226 (New England Patriots).
Football fans in the local markets can listen to the game on WGR 550 AM (SportsRadio 550) for the Rams and 98.5 The Sports Hub for the 49ers.
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Bills vs. Patriots start time
Date: Sunday, Oct. 5
Time: 8:20 p.m. ET
Bills vs. Patriots will kick off at 8:20 p.m. ET on Sunday, Oct. 5.
The game will be played at Highmark Stadium in Orchard Park, New York.
Bills 2025 schedule
Here is the full schedule for Buffalo.
Week Date Matchup Time (ET) TV/Live stream
1 Sept. 7 Bills 41, Ravens 40 — —
2 Sept. 14 Bills 30, Jets 10 — —
3 Sept. 18 Bills 31, Dolphins 21 — —
4 Sept. 28 Bills 31, Saints 19 — —
5 Oct. 5 vs. Patriots 8:20 p.m. NBC, Fubo, Peacock
6 Oct. 13 at Falcons 7:15 p.m. ESPN, Fubo
7 BYE — — —
8 Oct. 26 at Panthers 1 p.m. Fox, Fubo
9 Nov. 2 vs. Chiefs 4:25 p.m. CBS, Fubo, Paramount+
10 Nov. 9 at Dolphins 1 p.m. CBS, Fubo, Paramount+
11 Nov. 16 vs. Buccaneers 1 p.m. CBS, Fubo, Paramount+
12 Nov. 20 at Texans 8:15 p.m. Amazon Prime Video
13 Nov. 30 at Steelers 4:25 p.m. CBS, Fubo, Paramount+
14 Dec. 7 vs. Bengals 4:25 p.m. Fox, Fubo
15 Dec. 14 at Patriots 1 p.m. CBS, Fubo, Paramount+
16 Dec. 21 at Browns 1 p.m. CBS, Fubo, Paramount+
17 Dec. 28 vs. Eagles 4:25 p.m. Fox, Fubo
18 TBD vs. Jets TBD TBD
Patriots 2025 schedule
Here is the full schedule for New England.
Week Date Matchup Time (ET) TV/Live stream
1 Sept. 7 Las Vegas 20, Patriots 13 — —
2 Sept. 14 Patriots 33, Miami 27 — —
3 Sept. 21 Pittsburgh 21, Patriots 14 — —
4 Sept. 28 Patriots 42, Carolina 13 — —
5 Oct. 5 at Buffalo 8:20 p.m. NBC, Fubo, Peacock
6 Oct. 12 at New Orleans 1 p.m. CBS
7 Oct. 19 at Tennessee 1 p.m. CBS
8 Oct. 26 vs. Cleveland 1 p.m. FOX
9 Nov. 2 vs. Atlanta 1 p.m. CBS
10 Nov. 9 at Tampa Bay 1 p.m. CBS
11 Nov. 13 vs. New York 8:15 p.m. Amazon Prime Video
12 Nov. 23 at Cincinnati 1 p.m. CBS
13 Dec. 1 vs. New York 8:15 p.m. Prime Video
14 BYE — — —
15 Dec. 14 vs. Buffalo 1 p.m. CBS
16 Dec. 21 at Baltimore 1 p.m. CBS
17 Dec. 28 at New York 1 p.m. CBS
18 TBD vs. Miami TBD TBD
NFL schedule 2025: Week 5
Here's a complete look at the NFL schedule for Week 5 of the new season, with games spread out across three days.
Thursday, Oct. 2
Game Time (ET) TV/Live Stream
49ers 26, Rams 23 — —
Sunday, Oct. 5
Game Time (ET) TV/Live Stream
Vikings vs. Browns 9:30 a.m. NFL Network
Saints vs. Giants 1 p.m. CBS
Jets vs. Cowboys 1 p.m. FOX
Panthers vs. Dolphins 1 p.m. FOX
Ravens vs. Texans 1 p.m. CBS
Colts vs. Raiders 1 p.m. FOX
Eagles vs. Broncos 1 p.m. CBS
Cardinals vs. Titans 4:05 p.m. CBS
Seahawks vs. Buccaneers 4:05 p.m. CBS
Chargers vs. Commanders 4:25 p.m. FOX
Bengals vs. Lions 4:25 p.m. FOX
Bills vs. Patriots 8:20 p.m. NBC
Monday, Oct. 6
Game Time (ET) TV/Live Stream
Jaguars vs. Chiefs 8:15 p.m. ESPN
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