Warren is one of the Colts' top targets, especially on first down. He's tied with Ja'Marr Chase, Christian McCaffrey, and Garrett Wilson for sixth in the NFL with eight receptions on first down.
But the Cardinals might be the best team suited to face Warren.
"In camp we go against one of the best tight ends in the NFL with Trey," linebacker [Akeem Davis-Gaither](/team/players-roster/akeem-davis-gaither/) said. "We get a lot of practice at covering tight ends and we know what Warren likes to do in certain alignments and formations and stuff like that. We need to take it away and execute the play calls."
Safety [Jalen Thompson](/team/players-roster/jalen-thompson/) echoed Davis-Gaither's point, mentioning that "going against Trey is like going against a receiver," which can prepare them for Warren's versatility. Through five weeks, the Cardinals defense has only allowed a tight end to go over 50 yards twice.
The Colts offense has been firing on all cylinders. The relationship between quarterback Daniel Jones and wide receiver Michael Pittman Jr. has been smooth, as has Jonathan Taylor's remarkable start in the run game.
But there isn't room to ignore Warren.
"I think you know what type of plays you get when he's in the game and of course you know what type of plays you'd get when he's not in the game because he is the focal point," Davis-Gaither said. "There are some tells when he is in, when he is out, and as a defense as a whole, we got to study the film and execute it when those plays come up."
The game on Sunday will feature two of the rising stars at the position. But the Cardinals are hoping the conversation surrounds their Pro Bowl tight end going forward.
"Hopefully he doesn't have a good game this week," McBride said with a smile. "But I'm always pulling for him."