Arne Slot will be forced to ring around the changes in his first bid to salvage Liverpool's season in their Carabao Cup showdown with Crystal Palace.
The Dutchman has already seen his Reds side lose twice to the Eagles this year - the most recent of which started their current losing run.
New Liverpool signing called out after Brentford defeat and it's not Alexander Isak and Florian Wirtz
Slot was not happy with his team's performance as they were beaten again
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Slot was not happy with his team's performance as they were beaten againCredit: Getty
The Premier League champions fell to a penalty shootout defeat to Oliver Glasner's men in the Community Shield in August.
Liverpool responded to their Wembley setback by putting together a seven-match winning streak across three different competitions.
However, a last-gasp 2-1 loss at Selhurst Park on their reunion with Palace last month set the trend for the club's worrying recent form.
A3-2 defeat to Brentfordon Saturday night saw the Reds extend their Premier League losing streak to four games.
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Liverpool have been beaten five of their last six, if you include Champions League fixtures - having also had to come from behind during their sole victory during this period, a 5-1 win in Frankfurt.
For their third meeting against Palace, Slot is likely to hand a Reds debut in goal for Freddie Woodman, who joined on a free transfer.
Alisson Becker remains sidelined, which means Liverpool can't risk Giorgi Mamardashvili suffering any injury or suspension here.
The hosts also have fitness issues at right-back, with Jeremie Frimpong tweaking his hamstring in the Champions League last week.
That leaves Conor Bradley as the only recognised senior available at present, but his own injury record means he might not be risked.
Dominik Szoboszlai, who has covered at right-back, is in dire need of a respite, while Joe Gomez will be needed to fill in at centre-back.
Woodman could make his Liverpool debut after arriving on a free transfer from Preston North End
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Woodman could make his Liverpool debut after arriving on a free transfer from Preston North EndCredit: Getty
When did Calvin Ramsay last play for Liverpool?
The club's right-back problems could see the return of Calvin Ramsay, who last played a senior match for Liverpool nearly three years ago.
The forgotten Jurgen Klopp signing last played for the first-team in a penalty shootout victory over Derby in November 2022.
The one-cap Scotland international has since been hampered by injuries and has been loaned out to several EFL clubs and Kilmarnock.
This season, Ramsay has been confined to the U21's, captaining Rob Page’s side in three of his eight appearances for the youngsters.
Despite scoring in their 4-1 win over Everton, the defender was subbed in the 59th minute, likely to keep him fresh for the seniors.
Ramsay scored Liverpool's second goal during the PL2 game on Sunday
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Ramsay scored Liverpool's second goal during the PL2 game on SundayCredit: Getty
His only two senior appearances came in his maiden season over 1,000 days ago
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His only two senior appearances came in his maiden season over 1,000 days agoCredit: Getty
Giovanni Leoni's ACL injury in the Carabao Cup third round means Gomez will be needed to deputise in central defence.
The versatile former England international is likely to be partnered by Wataru Endo, with both Ibrahima Konate and Virgil van Dijk rested.
Andy Robertson and Milos Kerkez have traded starting berth roles at left-back in recent weeks, with the latter likely to get the nod here.
Elsewhere, Alexis Mac Allister is in need of game time having been reduced to substitute appearances against Frankfurt and Brentford.
Liverpool injury list
Alexander Isak - groin
Ryan Gravenberch - hamstring
Jeremie Frimpong - hamstring
Curtis Jones - groin
Alisson Becker - hamstring
Giovanni Leoni - ACL
Rio Ngumoha made his fourth Premier League appearance against Brentford
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Rio Ngumoha made his fourth Premier League appearance against BrentfordCredit: AFP
Fellow academy star Trey Nyoni has been waiting for another chance in the first-team
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Fellow academy star Trey Nyoni has been waiting for another chance in the first-teamCredit: Getty
Liverpool predicted XI vs Crystal Palace
Curtis Jones and Ryan Gravenberch both continue to nurse knocks, so Trey Nyoni will hope to gain first-team experience with another start.
Kieran Morrison, who joined his fellow academy star on the bench for Saturday's defeat to Brentford, will also hope to find himself in the XI.
Rio Ngumoha, like Nyoni, is expected to be a shoo-in to feature - having been introduced late on at the G-tech Community Stadium.
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Meanwhile, Federico Chiesa will replace Mohamed Salah on the right, with Alexander Isak's groin injury making him a doubt in attack.
With Jayden Danns out of action due to a hamstring injury, Hugo Ekitike - who got sent off in the last round - may have to lead the line.
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