CHARLOTTE — The Panthers entered the season with a deep and talented offensive line.
That depth is being tested this week.
Three starters were held out of Wednesday's practice, and a fourth was limited.
Right guard Brady Christensen (Achilles) has what Dave Canales called a "significant" injury that's expected to knock him out for the season.
But center Cade Mays (ankle/knee) and right tackle Taylor Moton (knee) were also listed as out, and Damien Lewis (oblique) was listed as a full participant.
The Panthers did get Chandler Zavala (knee) back on the field to start his 21-day window to practice as he works his way back from injured reserve. He was a full participant on Wednesday.