Premier League Matchday 10 will see Burnley host league leaders Arsenal, Tottenham take on Chelsea in a London Derby, and a struggling Liverpool will play against a resurgent Aston Villa at Anfield. Let’s get ready for these games and rest of the week’s fixtures with our Premier League predictions and picks for every match.
Brighton vs. Leeds United
American Express Stadium, 3:00p.m. GMT (11:00a.m. EDT), Saturday, November 1
After two successive defeats on the road to Manchester United and Arsenal, Brighton will host Leeds at the Amex. Fabian Hurzeler’s team have kept just one clean sheet in their last 22 matches in all competitions. If there’s ever a chance for the Seagulls to get their first clean sheet of the season, it would be here.
Leeds have been shut out in three of their four Premier League matches away from home this season. All three of their goals away from home came against Wolves in the Whites’ only away win of the season.
Brighton are inconsistent, but they should get a win here.
Brighton vs. Leeds Prediction: 2-0
Burnley vs. Arsenal
Turf Moor, 3:00p.m. GMT (11:00a.m. EDT), Saturday, November 1
Arsenal are top of the table, four points clear of second-place Bournemouth and a full seven points clear of reigning champions Liverpool. The Gunners’ defense has been the backbone of their success this season. Prior to playing a rotated squad against Brighton in the Carabao Cup on Wednesday, Arsenal had conceded just two shots on target in their prior four matches combined.
When you add in their set-piece proficiency, it’s hard to see the Gunners dropping points to Burnley this weekend. The Clarets have created the fewest expected goals (xG) in the Premier League this season (6.8) and have the league’s worst xG difference (-11.3).
Burnley vs. Arsenal Prediction: 3-0
Crystal Palace vs. Brentford
Selhurst Park, 3:00p.m. GMT (11:00a.m. EDT), Saturday, November 1
After starting the season high with a 19-match unbeaten streak dating back to last year, Crystal Palace have come crashing down to Earth. The Eagles managed to beat a weakened Liverpool in the League Cup, but lost three of their four prior matches — including a 0-1 defeat at home to Cypriot side AEK Larnaca in the UEFA Conference League.
The one common element in each of these losses for Palace was their inability to play their way. Oliver Glasner’s team excels when they can sit back and counter. When they can’t, they are pretty toothless.
Brentford won’t dominate possession — the Bees had just 34% of the ball in their 3-2 win over Liverpool last week — so it could be another tough day for Palace on Saturday.
Crystal Palace vs. Brentford Prediction: 1-1
Fulham vs. Wolves
Craven Cottage, 3:00p.m. GMT (11:00a.m. EDT), Saturday, November 1
Wolves are the most chaotic team in the Premier League right now. The West Midlands club have yet to win a league match this season, and have now lost three straight matches following their 3-4 Carabao Cup defeat to Chelsea on Wednesday.
Prior to that match, after their Matchday 9 loss to Burnley, Wolves head coach Vitor Pereira and Jørgen Strand Larsen got into a shouting match with fans that almost turned into a physical altercation.
Fulham staff and players aren’t clashing with fans (yet), but things aren’t well with the Cottagers at the moment either. Marco Silva’s side have lost four of their last five matches and currently sit 17th in the league table. However, three of those four losses were away from home — the other was a hard-fought match against Arsenal at Craven Cottage.
Playing Wolves at home should be a winnable match for Fulham.
Fulham vs. Wolves Prediction: 2-1
Nottingham Forest vs. Manchester United
The City Ground, 3:00p.m. GMT (11:00a.m. EDT), Saturday, November 1
Nottingham Forest suffered their fifth defeat in six games last Saturday, with a 2-0 defeat away at Bournemouth. Manchester United, meanwhile, won their third consecutive match after beating Brighton 4-2 at home.
Given these contrasting forms, it’s hard not to back Man Utd here. On the other hand, this Forest team is not the same one that struggled to score under Ange Postecoglou. If Sean Dyche can turn the Reds into even half of the counter-attacking team they were last season, they could do well here.
Nottingham Forest won all three of their Premier League matches against Man Utd under Nuno Espírito Santo, including a 1-0 win against the Red Devils at home last season.
Nottingham Forest vs. Manchester United Prediction: 1-1
Tottenham vs. Chelsea
Tottenham Hotspur Stadium, 5:30p.m. GMT (1:30p.m. EDT), Saturday, November 1
Tottenham are flying high after their 3-0 win over Everton on Matchday 9. The Lilywhites were the first team to win at the new Hill Dickinson Stadium this season and the first team to score a set-piece goal against the Toffees this year. However, Spurs home form has not been as stellar.
Thomas Frank’s side have won only one of their four home games in the league this year. That win was against lowly Burnley, who themselves won their first away match of the season just last week against Wolves.
Unlike Spurs, Chelsea are better on the road. The Blues are averaging more points away from home than at Stamford Bridge, despite playing arguably tougher competition. With this being said, Chelsea aren’t dominant away from home— they have a negative xG difference in away matches.
This should be a very competitive match with lots of goals. Chelsea have scored three goals or more in three of their last five trips to Tottenham Hotspur Stadium.
Tottenham vs. Chelsea Prediction: 2-2
Liverpool vs. Aston Villa
Anfield, 8:00p.m. GMT (4:00p.m. EDT), Saturday, November 1
With their 3-0 loss to Crystal Palace in the Carabao Cup on Wednesday, Liverpool have now lost six of their last seven matches and five straight against English opposition. The Reds are all the way down in 7th place and seven points behind Arsenal in the title race. Despite this poor form, Liverpool are favorites here, and for good reason.
Aston Villa have started winning games — they’ve won six of their last seven — but they aren’t creating chances like you’d expect. The Birmingham club still rank 19th in xG created and have created over 0.78 xG just once away from home this season. They also rank 17th in the Premier League for chances created,according to FotMob. Additionally, Unai Emery’s team hasn’t scored at Anfield since the 2022-23 season.
It’s hard to back Liverpool in their current form, but this could be a good opportunity for the Reds to get back on track.
Liverpool vs Aston Villa Prediction: 2-1
West Ham vs. Newcastle
London Stadium, 2:00p.m. GMT (9:00a.m. EST), Sunday, November 2
West Ham have failed to win any of their four matches since replacing Graham Potter with Nuno Espírito Santo in September. Following the Hammers’ 2-1 loss to Leeds on Matchday 9, the club have suffered three consecutive losses under the Portuguese manager.
Newcastle, on the other hand, have won five of their last six after beating Fulham 2-1 on Saturday and Tottenham 2-0 on Wednesday in the Carabao Cup. As impressive as the Magpies have been, it’s hard to trust this Eddie Howe team away from home. The Tyneside club have yet to win an away match in the league this season and have only scored one goal away from St James’ Park.
Talent should see Newcastle through this match, but it won’t be an easy fixture for them.
West Ham vs. Newcastle Prediction: 0-1
Manchester City vs. Bournemouth
Etihad Stadium, 4:30p.m. GMT (11:30a.m. EST), Sunday, November 2
Bournemouth continued their strong start to the season last weekend with a 2-0 win over Nottingham Forest. The Cherries now sit second in the table and are unbeaten in their last seven matches.
Manchester City had different fortunes on Matchday 9. Pep Guardiola’s team suffered a 1-0 defeat to Aston Villa. This match was the Sky Blues’ first loss since their 2-1 defeat to Brighton in August — they hadn’t even trailed in a match since that fixture.
Because of last weekend’s results, many EPL predictions this week have tipped the Cherries to upset City this weekend. We’re not convinced. Bournemouth lost this fixture 3-1 last season and have conceded at least three goals or more in each of their last three trips to the Etihad, including a 6-1 defeat in Andoni Iraola’s first season at the club.
Manchester City vs. Bournemouth Prediction: 2-1
Sunderland vs. Everton
Stadium of Light, 8:00p.m. GMT (3:00p.m. EST), Monday, November 3
We’re a quarter of the way through the 2025-26Premier League season and Sunderland are genuinely in the title race. The Black Cats jumped up to second place following their 2-1 win at Chelsea — they are just four points behind Arsenal.
Everton, meanwhile, are at risk of falling into a malaise after suffering their first home loss of the season last weekend, a 3-0 defeat to Tottenham. The Toffees have now lost four of their last six matches and have been shut out in three of their last five.
Sunderland have a negative xG difference and rank in the bottom half for goals scored, so there’s definitely a strong chance that their form falls off eventually. With Everton’s poor away record though, it’s hard to predict Sunderland to lose this match.
Sunderland vs. Everton Prediction: 1-0
Cody Aceveda
Cody Aceveda is a freelance writer based in Porto, Portugal. He has written for The Trivela Effect since February 2023. Cody is a fan of the Brighton, Portland Timbers, Portland Thorns, and Rayo Vallecano. He is also an experienced iGaming writer with over two years experience writing about sports betting and the sports betting industry for a variety of outlets.