Los Angeles Chargers superstar safety Derwin James suffered an ankle injury in the first quarter of Week 8 against the Minnesota Vikings and did not return for the remainder of the game. An MRI determined the four-time Pro Bowler avoided a major injury and is dealing with a low-ankle sprain. The mini BYE gave James a few extra days to rest and recover, giving him the best chance to play against the Tennessee Titans.
Los Angeles Chargers reveal game status of Elite 4x-Pro Bowler
Derwin James
Jul 24, 2024; El Segundo, CA, USA; Los Angeles Chargers safety Derwin James Jr. (3) speaks to the media after the first day of training camp at The Bolt. Mandatory Credit: Kiyoshi Mio-USA TODAY Sports
Derwin James was limited on Wednesday and upgraded to a full participant on Thursday and Friday. The Chargers released their Week 9 injury report, and the elite safety does not carry an injury designation against the Tennessee Titans. Therefore, James is active and will not miss any time as he continues to recover from a low-ankle sprain.
However, his backup won’t play
Los Angeles Chargers, Tony Jefferson
Oct 12, 2025; Miami Gardens, Florida, USA; Los Angeles Chargers safety Tony Jefferson (23) celebrates after intercepting a pass intended to Miami Dolphins wide receiver Jaylen Waddle (not pictured) during the first quarter at Hard Rock Stadium. Mandatory Credit: Sam Navarro-Imagn Images
Tony Jefferson suffered a hamstring injury in Week 8 and did not return for the remainder of the game. He was unable to practice this week, prompting the Chargers to rule Jefferson out. Meanwhile, rookie sixth-round pick R.J. Mickens is the top backup and the next man up in case of an emergency.
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