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NFL DFS Sunday main slate picks for Week 9

This article will focus on three players at each position using DraftKings’ pricing for the Sunday 1 p.m. slate. We will provide three pricing options: high, medium, and low, based on matchups and game theory, from top to bottom. Now that we’ve taken care of the housekeeping, let’s move on to week 9.

Quarterbacks

Patrick Mahomes

Kansas City Chiefs quarterback Patrick Mahomes (15) passes the ball against the Philadelphia Eagles during the fourth quarter of the game at GEHA Field at Arrowhead Stadium. Credit: Jay Biggerstaff-Imagn Images

Patrick Mahomes, Kansas City Chiefs ($7,100)

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Mahomes has a decent matchup this week on the road against the Bills. He is averaging almost 28 fantasy points per game over the last five games. Vegas has this game with the highest projected total on the slate. This game could become a shootout!

Daniel Jones, Indianapolis Colts ($6,200)

Jones has a good matchup this week against the Steelers. He is averaging more than 23 fantasy points per game over the last three games. Vegas has this game with the second-highest projected total on the slate.

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J.J. McCarthy, Minnesota Vikings($4,900)

McCarthy has a tough matchup this week on the road against the Lions. He’s missed the last five starts due to injury. This is a little bit of a dart throw. Consider McCarthy a GPP play!

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Running Backs

Oct 19, 2025; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates after a touchdown during the second quarter against the Atlanta Falcons at Levi’s Stadium. Mandatory Credit: Kyle Terada-Imagn Images

Christian McCaffrey, San Francisco 49ers ($8,800)

McCaffrey has a good matchup on the road against the Giants. He is averaging more than 25 fantasy points per game over the last five games. Vegas has this game with the third-highest projected total on the slate.

Jahmyr Gibbs, Detroit Lions ($8,000)

Gibbs has a great matchup at home against the Vikings. Last season, he averaged 42 fantasy points per game against the Vikings. Gibbs could be a lock!

RB Kimani Vidal, Los Angeles Chargers ($6,300)

Vidal has a great matchup on the road against the Titans. The Titans’ defense has allowed 24 fantasy points per game to opposing RBs over the last five games.

Wide Receivers

Detroit Lions wide receiver Amon-Ra St. Brown celebrates the 31-23 win over the Tampa Bay Buccaneers

Detroit Lions wide receiver Amon-Ra St. Brown celebrates the 31-23 win over the Tampa Bay Buccaneers in the NFC divisional round at Ford Field in Detroit on Sunday, Jan. 21, 2024. His hair is dyed blue. | Junfu Han / USA TODAY NETWORK via Imagn Images

Amon-Ra St. Brown, Detroit Lions ($8,300)

St. Brown has a great matchup this week at home against the Vikings. He is averaging almost 26 fantasy points per game over the last four games against Minnesota. Consider St. Brown a GPP play!

Rashee Rice, Kansas City Chiefs ($7,600)

Rice has a good matchup this week on the road in Buffalo. He’s averaging 24 points per game this season. The Bills are allowing more than 26 fantasy points per game to WR1 over the last three games.

Khalil Shakir, Buffalo Bills ($5,300)

Shakir has a decent matchup at home against the Chiefs. He is averaging 14 fantasy points per game over the last three games against Kansas City. Consider Shakir a value play!

Tight Ends

Oct 26, 2025; Indianapolis, Indiana, USA; Indianapolis Colts tight end Tyler Warren (84) rushes during the third quarter against the Tennessee Titans at Lucas Oil Stadium. Mandatory Credit: Robert Goddin-Imagn Images

Tyler Warren, Indianapolis Colts ($5,500)

Warren has a great matchup this week on the road in Pittsburgh. He is averaging 15 fantasy points per game over the last five games. The Steelers’ defense is allowing almost 19 fantasy points per game to opposing TE1s over the last five games.

Brock Bowers, Las Vegas Raiders ($5,000)

Bowers has a good matchup this week at home against the Jaguars. Last season week 16, he had 13 targets, 11 receptions, and 99 receiving yards against Jacksonville.

T.J. Hockenson, Minnesota Vikings ($3,400)

Hockenson has a good matchup this week on the road against Detroit. The Lions are ranked 26th against the TE1 position. Consider Hockenson a value play!

Defenses

Oct 19, 2025; London, United Kingdom; Los Angeles Rams linebacker Josaiah Stewart (10) and linebacker Jared Verse (8) reacts after a play against the Jacksonville Jaguars during the second half of an NFL International Series game at Wembley Stadium. Mandatory Credit: Kirby Lee-Imagn Images

Los Angeles Rams ($3,900)

The Rams’ defense is averaging 14 fantasy points per game over the last two games. They should control this game against the struggling Saints’ offense.

Jacksonville Jaguars ($3,300)

The Jaguars’ defense struggled in week 7 against the Rams. But they are coming off their bye week, and the Raiders are not the Rams.

Houston Texans ($2,900)

The Texans’ defense has been averaging almost 13 fantasy points per game over the last four games. I like their chances at home against the Denver offense.

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