While most games involving the Kansas City Chiefs are considered "must-watch" affairs, the truth is that every Chiefs-Bills contest takes things to another level. This year, both teams are fighting in competitive divisions while aiming for conference supremacy, which makes their head-to-head match about more than just edges in playoff seeding.
Each team has considerable star power, beginning at the quarterback position. Can Josh Allen get the best of the Chiefs once again in the regular season? Can Patrick Mahomes earn a win before the postseason against the Bills? Can Buffalo stop K.C.'s high-octane passing attack? Will James Cook run over the Chiefs like has everyone else?
Here are our predictions for Week 9's matchup between the Chiefs and Bills in Buffalo.
**Christian Ainsworth**
The Chiefs skate into the bye week with a win against a battered and bruised Bills team. The Bills try to make a statement by involving Keon Coleman early, but the Chiefs' defensive backs hold strong and deliver a dominant performance. **Chiefs 27, Bills 21**
**Price Carter**
It's hard to predict anything but a tight game between the Bills and Chiefs. Strangely enough, this feels like the first time in a long time that the Chiefs come into this matchup as the hotter team. The worst unit in this game is by far the Bills' defense, which is now missing its best player (Ed Oliver). The Chiefs' offense feels primed to take advantage of this matchup, and the Chiefs' defense can hopefully do enough to limit Josh Allen and James Cook. Look for turnovers or stops on 4th downs to be the difference in this game. **Chiefs 27, Bills 24**
**Matt Conner**
The Chiefs have found their mojo, to be sure, but that doesn't mean they're unstoppable. Washington slowed them considerably for a full half, and they've played a lot of bad quarterbacks in recent weeks. I think Josh Allen gets the home-field advantage here and James Cook lives up to his last name. **Bills 30, Chiefs 23**
**Bransen Gibson**
We're in for a good ol' fashioned shootout. The Chiefs offense has been on a roll, and against an ordinary Buffalo defense, I think they'll feast. Josh Allen and James Cook are the real deal, however, and the Chiefs have always struggled to stop them. Both teams will score plenty of points, but the Chiefs will score more. Chiefs 34, Bills 31
**Braden Holocek**
You can argue that the Chiefs and the Bills have both been up and down defensively. There are open plays against each defensive unit each week. In a game that could turn into a shootout, Kansas City has a deeper cast of weapons. The skill players have all been steadily showing up for the Chiefs. That is the difference in a trip to Buffalo this time around. **Chiefs 27, Bills 23**
**Scott Loring**
The Chiefs’ ability to stop the run will be the difference-maker in the flow of this game. But ultimately, the Bills rely too heavily on one man while Kansas City has too many playmakers on offense.After this many matchups, Steve Spagnuolo knows how he wants to contain Josh Allen. I like the Chiefs to win this pivotal matchup. **Chiefs 36, Bills 30**
**Greg Morse**
Oh no! The Chiefs have a losing record to the Bills in the regular season—in the Josh Allen era. Anyways. The Bills' defense is not good, and Mahomes and Co. will (should) dice them up. The question is: can the Chiefense stop the Bills? They’ve been on a heater recently, with only 7 points total in the last 8 quarters of gameplay. Josh Allen is a tad better than Geno Smith and Marcus Mariota, but I still think Spags will be in his bag. **Chiefs 28, Bills 10**
**Shawn O'Brate
**This is the week of the schedule that's somehow always circled yet never seems to go the Chiefs' way for some reason. The Bills, off a bye week, are going to go scorched earth on Kansas City, which means the bend-don’t-break defense that Spags has masterfully put together this year is going to have its hands full right off the bat. Luckily, the Chiefs' offense is the best it’s been in half a decade, which means this goes right down to the wire like always. Butker kicks a game-winning FG with time expiring to send Buffalo fans home sad once again. **Chiefs 34, Bills 31**
**Charles Robinson**
This Week 9 matchup, or as Bills fans refer to it - the Super Bowl, has all the excitement you could ask for in a regular season game. Does the law of averages prevail in our assumption that the Bills just have the Chiefs' number in the regular season, but the Chiefs will once again take the cake when it matters? Or is the healthy version of the 2025 Chiefs too much for an ailing Bills defense to manage? Josh Allen will inevitably be fired up, as will Patrick Mahomes. I like the Chiefs to stay hot and finally steal Buffalo's regular-season thunder behind a big game from the eventual MVP, Patrick Mahomes. **Chiefs 37, Bills 33**
**Lucas Strozinsky**
For the first time in years, the Chiefs are firing on all cylinders on both sides of the ball. They will go into Orchard Park and leave with their first regular season win versus the Bills in over 5 years. **Chiefs 33, Bills 25**