The San Francisco 49ers notched another win on Sunday, moving to 6-3 after defeating the New York Giants 34-24. While winning has been a theme for the Niners this season, so have significant injuries. Unfortunately, San Francisco experienced both in Week 9.
The major injury in this game happened to Mykel Williams, who is feared to have suffered a torn ACL.
The rookie edge defender will be the latest key player the 49ers lose for the season, and also the latest edge in San Francisco to go down with an injury. The Niners were already thin at that position and were expected to acquire an edge defender ahead of the trade deadline, but now they may be forced to make a trade if Williams is out for the remainder of the year.
#49ers edge Mykel Williams, their first-rounder, is feared to have torn his ACL, coach Kyle Shanahan told reporters. A brutal season at this spot. MRI coming. pic.twitter.com/RML81LnFRW
— Ian Rapoport (@RapSheet) November 2, 2025
Mykel Williams' injury could force 49ers to trade for an edge defender
Early in the season, San Francisco lost perennial Pro Bowler and 2022 Defensive Player of the Year Nick Bosa to an ACL injury. Bosa’s absence put a strain on the group, and that strain was intensified when Bryce Huff went down with a hamstring injury in Week 7. Huff is expected to return this year, but he has missed the last two games, leaving the 49ers without much of a pass rush.
Now, Williams has joined his veterans on the injury report, and San Francisco has no choice but to add a veteran edge defender. Fortunately for the Niners, there are options. The most likely options both play for the Miami Dolphins, who have officially opened up for business after falling to 2-7 and firing their general manager. Outside linebackers Bradley Chubb and Matthew Judon are both trade candidates, and San Francisco could actually use both of them.
With the trade deadline on Tuesday, Nov. 4, the 49ers will surely be active up until that point.
San Francisco clearly has a competitive team, so it needs to try and fill the gaps while it can.