Welcome to week 10 of the NFL season! It is always fun to take a look at bold predictions every week, seeing what comes true, what is way off, and what comes close. Here is one bold prediction for every AFC team this week! What is your bold prediction for the week?
AFC East:
Oct 5, 2025; Orchard Park, New York, USA; Buffalo Bills running back James Cook (4) rushes the ball against the New England Patriots during the first half at Highmark Stadium. Mandatory Credit: Gregory Fisher-Imagn Images
Buffalo Bills:
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RB James Cook rushes for over 150 yards and two touchdowns against the Miami Dolphins.
WR Keon Coleman catches a 45-yard touchdown pass.
New England Patriots:
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The running backs rush for over 140 yards and two touchdowns against the Bucs 7th-ranked rush defense.
Miami Dolphins:
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RB De’Von Achane catches 8 passes for 55 yards and a touchdown and rushes for 85 yards.
New York Jets:
The offense scores just 10 points, and Justin Fields is sacked 5 times.
AFC South:
Oct 19, 2025; Inglewood, California, USA; Indianapolis Colts quarterback Daniel Jones (17) throws the ball in the second half against the Los Angeles Chargers at SoFi Stadium. Mandatory Credit: Gary A. Vasquez-Imagn Images
Indianapolis Colts:
Daniel Jones struggles for a second straight week, turning the ball over twice and getting sacked 4 times.
TE Tyler Warren goes over 100 receiving yards and scores a touchdown.
Houston Texans:
The Texans defense forces 3 turnovers against Trevor Lawrence and the Jaguars.
Jacksonville Jaguars:
Travis Etienne is held under 50 total yards and fumbles in the red zone.
Tennessee Titans: Bye Week
AFC North:
Sep 28, 2025; Kansas City, Missouri, USA; Baltimore Ravens quarterback Lamar Jackson (8) scrambles during the first half against the Kansas City Chiefs at GEHA Field at Arrowhead Stadium. Mandatory Credit: Jay Biggerstaff-Imagn Images
Baltimore Ravens:
Lamar Jackson throws for over 300 yards against the Vikings 8th-ranked pass defense.
Cleveland Browns:
Rookie TE Harrold Fannin Jr. goes over 100 receiving yards and scores a touchdown.
QB Shedeur Sanders plays in the second half and throws a touchdown pass.
Pittsburgh Steelers:
The defense struggles again after finally showing up a week ago against the Colts.
Cincinnati Bengals: Bye Week
AFC West:
Denver Broncos
Denver Broncos quarterback Bo Nix (10) makes a pass against the Dallas Cowboys in the first quarter at Empower Field at Mile High. Credit: Ron Chenoy-Imagn Images
Denver Broncos:
Bo Nix has 400 total yards and three total touchdowns in a blowout win over the Raiders on TNF.
Los Angeles Chargers:
RB Kimani Vidal bounces back from a rough week 9 with 85 rushing yards and a touchdown.
Las Vegas Raiders:
Geno Smith throws 3 interceptions and is benched in the second half on TNF.
Kansas City Chiefs: Bye Week
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