The Chargers took a 12-3 lead into the break and added to the advantage in the third quarter when Cameron Dicker hit a 59-yard field goal that tied his career long.
The Bolts defense, which was lights out all game, came up big early in the fourth quarter with a red-zone stop against Pittsburgh.
The Steelers kept their offense on the field on fourth-and-6 from the 10-yard line, but Cam Hart won against DK Metcalf and tallied a pass breakup to force a turnover on downs.
The Chargers offense, holding a 15-3 lead, then put an exclamation point on the game with a six-play, 90-yard scoring drive.
The sequence was highlighted by a 58-yard pass play to McConkey before Kimani Vidal scored on a 2-yard touchdown run to give the Chargers a 22-3 lead.
The Chargers defense kept the pressure on the Steelers as Rodgers was intercepted by Donte Jackson on the ensuing drive.