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Jaguars vs Chargers key matchups: run game to get back on track?

Travis Etienne vs Daiyan Henley

There’s no easy way to say this; the Jaguars offense STUNK last week against the Houston Texans. Despite having a 19-point lead heading into the fourth quarter, much of Jacksonville’s scoreboard dominance came from early turnovers forced by the defense, opportunities that Trevor Lawrence & co largely couldn’t convert into touchdowns and the team had to settle for field goals. And when it mattered, the Jags couldn’t move the football

The run game, fairly consistent this season, was also underwhelming on Sunday. Travis Etienne will be determined to improve on a 58-yard performance that saw him post just 3.6 yards per carry. We know that this offense typically goes how their ground game goes - in order to unlock the under-fire Lawrence his lead running back will have to deliver.

The Texans have an elite defense, and so do the Jags’ next opponents. The Chargers are coming off the back of a strong Sunday Night Football performance where they held the Pittsburgh Steelers to just 234 yards of offense. That being said, Jaylen Warren showed you can run on this defensive front with 70 yards from just 14 carries. Trying to bottle up Etienne will be third-year linebacker Daiyan Henley, who leads the Chargers this season with 67 tackles. Henley’s season is all the more impressive considering the recent death of his brother. Etienne will need to have a big day for the Jaguars to win this game.

Jarrian Jones vs Ladd McConkey

Since joining the team in free agency, Jourdan Lewis has been one of the standout performers on a spicy Jaguars defense. A neck injury sustained against the Las Vegas Raiders meant the nickel corner was absent for last week’s game against the Texans. In his absence Jarrian Jones stepped in and did well; the versatile defensive back making four tackles, two pass breakups and recording an interception on the first drive of the game. With Lewis’ outlook no clearer as of Wednesday, expect Jones to deputise in the slot once again.

Jones will have his hands full in Week 11. Ladd McConkey might only be in his second year, but he’s immediately become one of the most devastating slot receivers in the NFL. After racking up 1,149 yards as a rookie he’s continued to terrorize defenses this season - and posted his best stat line of 2025 last Sunday, turning four catches into 107 yards and a touchdown. Justin Herbert is an elite quarterback in his own right, but having a weapon like McConkey at his disposal makes his job a hell of a lot easier.

The Jags will be hoping that Jones can make a similar impact this weekend as they try to control this explosive Chargers passing game.

Travon Walker vs Trey Pipkins

If there’s one weakness to this Chargers team, it’s the right side of their offensive line. Devastating injuries to Rashawn Slater and Joe Alt have seen Los Angeles move pieces around in order to try and keep Justin Herbert upright. The results have been, as you might imagine, inconsistent at best. According to PFF, right tackle Trey Pipkins, right guard Mekhi Becton and center Bradley Bozeman rank near to or right at the bottom of their respective positions when it comes to grades. The Chargers appear to have survived thus far despite this vulnerability, but the Jaguars have the tools to attack them on Sunday.

There were doubts as to whether Travon Walker was worthy of the number one overall pick in the 2022 NFL Draft. But since his rookie season Walker has elevated his game on an almost weekly basis, and now affects offenses every Sunday. Two back to back 10-sack seasons justify Trent Baalke’s selection (remember him?), and he’ll be chomping at the bit to get after Herbert this weekend.

If Walker can put the right side of that line on skates, the Jaguars have a chance to upset the odds and earn their sixth win of the season.

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