Several key fantasy football players left their Week 11 games with injury and did not return, including Michael Penix Jr., Drake London, Dillon Gabriel and Josh Jacobs
19:33 ET, 16 Nov 2025
Atlanta Falcons wide receiver Drake London runs with the ball
View 2 Images
Drake London was injured late in regulation of the Falcons' overtime loss to the Panthers in Week 11(Image: Photo by Jonathan Bachman/Getty Images)
Sunday in NFL Week 11 saw several high profile players, including three starting quarterbacks and two premier skill position players, leave their game with injuries and not return.
Those names include Atlanta Falcons quarterback Michael Penix Jr. (knee) and wide receiver Drake London (knee), Cleveland Browns quarterback Dillon Gabriel (concussion), Pittsburgh Steelers quarterback Aaron Rodgers (hand), and Green Bay Packers running back Josh Jacobs (knee).
Article continues below
Here, we assess the injury statuses of each player and the impact they have on fantasy football before presenting potential replacement options if any players are to miss time with the injuries they suffered in Week 11.
Article continues below
READ MORE: Shedeur Sanders makes NFL debut for Browns after Dillon Gabriel can't return for second half vs RavensREAD MORE: Buffalo Bills star risks NFL fine with questionable touchdown celebration
Michael Penix Jr.
Penix Jr. injured his knee in the third quarter of the Falcons’ overtime loss to the Carolina Panthers and did not return.
If he misses time, Atlanta will turn to Kirk Cousins at QB. Head coach Raheem Morris noted after the loss “there was a chance Penix could come back in the game,” indicating it may not be a serious injury.
As the 25th-ranked quarterback in fantasy, Penix Jr. isn’t owned or started in many leagues and is easily replaceable if you own him.
Drake London
London was ruled out with a knee injury late in regulation in the Falcons’ loss to the Panthers, a development with major fantasy ramifications.
London is the sixth-ranked wide receiver in fantasy this season and has logged three straight 100+ yard games. If he misses time, replacing him on your team will be near impossible.
Fellow Falcons pass catchers Darnell Mooney and Kyle Pitts rise in value if London can’t go next week.
Cleveland Browns quarterback Shedeur Sanders throws the ball during his NFL debut
View 2 Images
Shedeur Sanders played his first NFL regular season snaps in relief of the injured Dillon Gabriel(Image: Photo by Nick Cammett/Getty Images)
Dillon Gabriel
Gabriel (concussion) was ruled out to start the second half of the Browns’ Week 11 game against the Baltimore Ravens, and was replaced by Shedeur Sanders.
It marked the first regular season snaps of Sanders’ career, and presents the possibility of the high profile draft pick becoming a legitimate fantasy football option.
In five full games as a starter, Gabriel scored an average of 12.9 fantasy points per game.
Aaron Rodgers
Rodgers suffered an injury to his non-throwing hand late in the first half of the Steelers’ 34-12 win over the Bengals and did not return.
The 41-year-old is currently QB18 fantasy and is considered a fringe starting option, so if he misses time, there should be no issue replacing him.
READ MORE: Buffalo Bills star risks NFL fine with questionable touchdown celebrationREAD MORE: Chicago Bears star pays tribute to Last Chance U Coach Beam days after he was shot dead
Under-owned options to replace him include Jordan Love, Trevor Lawrence and Tua Tagovailoa.
Josh Jacobs
Jacobs left Sunday’s win over the New York Giants in the second quarter with an apparent left knee injury.
The Packers’ star running back seemingly hit his left knee on the ground and briefly returned to the game before being ruled out.
Article continues below
Jacobs entered Week 11 as the sixth-highest scoring RB in fantasy, so this injury may come as a major blow to his owners. Emanuel Wilson, who rushed 11 times for 40 yards in relief of Jacobs, will take over as Green Bay’s starting running back if Jacobs misses time.