Chiefs’ power back Isiah Pacheco is out again, and Kansas City will lean on Kareem Hunt and an elevated Clyde Edwards-Helaire. The team also cleared two question marks: LG Kingsley Suamataia and WR Xavier Worthy are active. Reported November 23, 2025, by Tod Palmer at KSHB, this shakes Kansas City’s game plan against the Colts and forces quick roster math at running back.
“Isiah Pacheco will miss his third straight game after suffering a knee injury late in the Chiefs’ win against the Washington Commanders late last month,” reported Tod Palmer, KSHB.
RB Isiah Pacheco is out again, but LG Kingsley Suamataia and WR Xavier Worthy are active against the Colts.
Photo: Reed Hoffmann/AP@todpalmer reports: https://t.co/OKtBzTQyUa pic.twitter.com/hTKos3CdHR
— KSHB 41 News (@KSHB41) November 23, 2025
Isiah Pacheco Injury Update Reshapes Kansas City Chiefs’ Offensive Plan
NFL: Las Vegas Raiders at Kansas City Chiefs
Kansas City Chiefs Loses Isiah Pacheco for Week 9 Clash Against Buffalo (Credit: Denny Medley-Imagn Images)
Losing Isiah Pacheco again changes the identity of the offense for the day. According to the Injury Update, he is out with a knee complication that can be traced back to the Week 8 victory over the Washington Football Team. Kareem Hunt is going to bear the early-down workload. The Chiefs promoted Clyde Edwards-Helaire to the practice squad in case.
Kingsley Suamataia, who is a left guard, is questionable due to a concussion but has passed protocol and is active, which is a victory for both run blocking and pass protection. Wideout Xavier Worthy (ankle concern) is also active, giving Andy Reid another vertical option. Tod Palmer’sKSHB report confirmed both activations..
Elijah Mitchell, who was active last week, is inactive again so that the backfield snaps will skew toward Hunt and the 2020 first-round veteran Edwards-Helaire. That elevates pass-protection tasks for the offensive line and forces more receiving responsibility onto Travis Kelce and Worthy on early downs. The Colts’ front-seven will try to test that new plan, except for short-yardage packages and more shotgun handoffs to mitigate Pacheco’s absence.
Pacheco’s injury has been treated on a week-to-week basis; this Isiah Pacheco Injury Update doesn’t provide a firm return date. The clarity today is tactical: Suamataia and Worthy being active stabilizes the Chiefs’ lineup, while Pacheco’s absence hands more decisive carries to Hunt and Edwards-Helaire.
The Chiefs are managing injuries instead of curing them. This Isiah Pacheco Injury Update is a hit to Kansas City’s smash-mouth plans, but the active return of Suamataia and Worthy gives Reid some tools to mask the loss.