Chelsea and Barcelona have a long and well-documented history in the Champions League, and are set to write another chapter at Stamford Bridge.
The Blues are looking to move towards the top eight of the groups, with plenty of their individuals desperate to impress against one of the best sides in Europe.
Chelsea have plenty of iconic moments against Barcelona, however not all of them have gone in their favour.
Will Chelsea beat Barcelona in the Champions League?
A classic semi-final second leg at Stamford Bridge saw the Blues eliminated from the competition, with a fingers pointed at dubious refereeing decisions that robbed the Blues of a number of penalties.
Chelsea v Barcelona - UEFA Champions League Semi Final
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Andres Iniesta was stunned he could score iconic goal past Petr Cech
It was a brilliant strike from Andres Iniesta in the final moments which caused heartbreak in West London, with many surprised that Barcelona had finally found the breakthrough.
Even the midfielder himself was shocked that he was able to find the net. He told The Athletic that he was surprised he had managed to pull off a shot that could beat Petr Cech.
He said: “There was no clear idea. Once I was there, I was outside the area in case the cross was cleared and went out. I remember when Leo tried to make space to shoot and the Chelsea players came out and left him behind.
“Then the shot was spectacular, the only place I think it could have gone. Besides, Petr Cech is a goalkeeper who is practically two metres tall. It was almost impossible for that ball to go in. It was a crazy moment.”
Chelsea were denied the chance of making it to their second successive Champions League final against Manchester United.
Champions League, Finale 2012, Bayern München - Chelsea 4:5
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Chelsea’s iconic rivalry with Barcelona
Chelsea are actually on a run of losing just one of their last 10 games against Barcelona, which have been packed with drama over the years.
What the big names have said in the past about Chelsea vs Barcelona
“There are players here who hate Chelsea more than Real Madrid. I never thought I would hear myself say that. I also never thought I would see something worse than the Boca and River Plate rivalry or Brazil v Argentina – but this is. We would rather play Arsenal, Manchester United or anyone else than be on the pitch with Chelsea.”
Lionel Messi
“I thought this could be the worst night of my footballing life, I was thinking towards double figures, I spent the first 20 minutes getting nowhere near Xavi and Iniesta”
Frank Lampard
“I always say this Barcelona team was the best of my generation, one team was capable of matching them in this era and that was us.”
John Terry
Arguably the best player of all time, Lionel Messi famously struggled when playing against Chelsea, seeing them become one of his least-favoured opponents.
Now, it is the time of new superstars such as Estevao Willian and Lamine Yamal to add their own moments of brilliance to this iconic feud.
With Cole Palmer likely to be absent, the Blues will be looking for someone else to step up and create magic in the Champions League.