While we’re still picking up the pieces from a packed slate last weekend, there’s a lot to look forward to on the NFL Week 13 schedule too. This week, there are 16 NFL matchups to preview, featuring all 32 teams in action.
Below, we dive into one bold prediction for each game on the Week 13 NFL schedule, from Thursday to Monday.
Related: NFL Power Rankings 2025: Week-by-Week NFL Evaluations of All 32 Teams
Packers Embarrass Lions with 20-Point Win
NFL
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Playing on Thanksgiving is an annual tradition for the Lions. Last year, they delivered a 23-20 win over their division rival, the Bears. They won’t get as lucky this time around as the Packers put together their most impressive win of the season in primetime with millions of people watching.
Related: 2025 NFL QB Rankings: Week 13 Edition
Cowboys Hold Chiefs to Under 15 Points
NFL: Arizona Cardinals at Dallas Cowboys
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The Chiefs’ offense has been much better as of late, racking up over 400 yards in three of their past five games. Meanwhile, Dallas’ defense has improved since the trade deadline too, allowing just 18.5 points per game. If Dallas wants to make a playoff push, they’ll have to beat the good teams, and it starts on Thanksgiving.
Joe Burrow’s 400-Yard Day Leads Bengals Past Ravens
NFL: Jacksonville Jaguars at Cincinnati Bengals
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After missing the past nine games due to injury, Joe Burrow is back in action on Thursday. We expect him to be at his best. The Ravens have been excellent defensively as of late, but Burrow’s Bengals are hungry for a win after losing the past four games. With everything on the line, the Bengals will put on an incredible offensive performance to keep whatever playoff hopes they have alive for another week.
Saquon Barkley Busts Out 130 Yards in Eagles Win Over Bears
NFL: Philadelphia Eagles at Dallas Cowboys
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It’s no secret that Saquon Barkley isn’t having as much success as he got used to last year in Philadelphia. He’s had just one 100-yard game all year. He had 11 last season. But opportunity is knocking this week against a Chicago defense that ranks 30th in rushing yards per attempt.
Shedeur Sanders’ 300-Yard Game Fuels Browns Past 49ers
NFL: Cleveland Browns at Las Vegas Raiders
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Last week Sanders got to make his starting debut after seeing first-team action during practice for the first time all season. With more reps, we should see him continue to improve. He’ll get another decent opportunity against San Francisco’s bottom-tier pass defense. Another strong performance, like a 300-yard game will put Sanders in the good graces of any of his remaining haters.
Cam Ward’s 3 TD Game Spoils Jaguars’ Day
NFL: Seattle Seahawks at Tennessee Titans
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The No. 1 pick has been a bit better as of late, where he’s learning to take advantage of his mobility. Last week he had the first multi-touchdown game of his career, getting one by air and by ground. But the Titans are still seeking their second win of the season. Jacksonville has shown they’re mistake-prone, and that could help Cam Ward put together a stronger performance.
Texans Shut Out Colts in Statement Win
NFL: Houston Texans at Tennessee Titans
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Houston has the league’s best defense for most of the season. They slipped to second last week, but they’ve managed to stifle some of the top scoring offenses in football. Meanwhile, Indianapolis has also had a top offense all year long, they actually enter Week 13 ranked first in scoring. Thus, if the Texans want to make a statement, they’ll find a way to limit the Colts to under 20 points, but we’ll go as far as to say they’ll find a way to shut the Colts out.
Saints Score Season-High 30 Points in Win Over Dolphins
NFL: New Orleans Saints at Carolina Panthers
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The Saints have an offensive-minded head coach, yet they haven’t topped 26 points all season long. Tyler Shough is just three starts into his career, so the potential for rapid growth is there, especially against a Dolphins team that hasn’t quite been right all year long either.
Bijan Robinson’s 150-Yard Game Lifts Falcons Past Jets
NFL: Atlanta Falcons at New Orleans Saints
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We can’t imagine how ugly the Falcons’ offense would look if they didn’t have Bijan Robinson this season. He’s accounted for 38.4% of the team’s yards this season. We’d expect another big game this week against a Jets defense that is still looking for their first interception. Robinson’s big game should lead to an easy win for the Falcons.
Teddy Bridgewater’s 3 TD Day Leads Bucs Past Cardinals
NFL: Tampa Bay Buccaneers at Los Angeles Rams
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Baker Mayfield’s shoulder injury could keep him out of action Sunday. That could be bad news for the Buccaneers, but they’re in good hands with the veteran Teddy Bridgewater. Though, it’s been four seasons since the 33-year-old has started a game. Of course, Bridgewater also spent part of that time as a coach, so if he has enough time to prepare, he should be more than ready for the challenge ahead.
Tetairoa McMillan’s 100-Yard Game Helps Panthers Beat Rams
NFL: Carolina Panthers at Atlanta Falcons
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Tetairoa McMillan, combined with Bryce Young’s continued growth, have helped transform this offense. The question is, are they ready to take down the NFL’s best defense? It would be arguably the biggest win of Young’s NFL career yet, but he could do so by funneling a heavy dose of targets to his new star receiver.
Max Brosmer’s 300-Yard Game Helps Vikes Beat Seahawks
NFL: Cincinnati Bengals at Minnesota Vikings
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J.J. McCarthy emerged from last week’s loss with concussion symptoms, so we’d imagine the Vikings won’t rush their first-round QB back into action, especially after his poor play. Turning to their backup, undrafted rookie Max Brosmer isn’t ideal either, but the Vikings do love the University of Mnnesota product. The real shocker here would be if Brosmer can immediately outperform McCarthy while stealing a victory away from their QB from last season, Sam Darnold.
DK Metcalf’s 3 TD Game Lifts Steelers Past Bills
Syndication: The Enquirer
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The Steelers essentially swapped George Pickens for DK Metcalf before the season started, and it’s looked like a terrible mistake thus far. But DK Metcalf is certainly capable of taking over a game if given enough opportunities. The Steelers may have to funnel more targets his way if they hope to keep up with Josh Allen’s scoring attack and few teams have a player capable of handling the physicality that the 6-foot-4, 229-pound Metcalf presents.
Raiders Score 35 Points in Big Win Over Chargers
NFL: Cleveland Browns at Las Vegas Raiders
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The Raiders were tired of the incompetence of ranking second-worst in scoring, while averaging the fewest yards per carry in the NFL. That shouldn’t happen with Ashton Jeanty so clearly something needed to change. With little left to play for, we could see the shackles come off this week and it’d come at a perfect time against an elite Chargers D.
Croskey-Merritt”s 100-Yard Game Helps Commanders Beat Broncos
NFL: Washington Commanders at Los Angeles Chargers
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The Commanders need a hero this week if they want to take down the red-hot Broncos, who have won nine in a row. Jacory Croskey-Merritt has flashed star talent, but he hasn’t gone over 50 yards from scrimmage in the past five games. That changes this week in a game Denver could be overlooking.
Giants Sack Drake Maye 5 Times, Get Big Win for Mike Kafka
NFL: Philadelphia Eagles at New York Giants
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Drake Maye is emerging as an MVP candidate in his second season as a pro, helping the Patriots win their past nine games. Meanwhile, the Giants are a shell of what they should be after injuries have knocked their two best playmakers out for the season. Yet, Dexter Lawrence, Brian Burns, and Kayvon Thibodeaux can still find some joy in wrecking the Patriots’ day by sacking Maye five times in a win that gives Giants fans a glimpse of what it’s like to have a good defense again.
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Sports fan since birth. I am also passionate about cars, music, and anything funny. Minnesotan, born and raised. Maybe ... More about Andrew Buller-Russ