NOW PLAYING video Jordon Love zips tight window throw to Christian Watson for 17 yards on second play of game Green Bay Packers quarterback Jordon Love completes a 17-yard pass to wide receiver Christian Watson on the second play of the game against the Detroit Lions.
NOW PLAYING video Barrett Carter leads Bengals charge to halt Pats 'Tush Push' attempt on third down Cincinnati Bengals linebacker Barrett Carter leads Bengals charge to halt the New England Patriots "Tush Push" attempt on third down.
NOW PLAYING video Jaylen Reed locates Shakir's fumble for key fumble recovery Houston Texans safety Jaylen Reed locates Buffalo Bills wide receiver Khalil Shakir's fumble for key fumble recovery.
NOW PLAYING video Top catches | Week 12 Watch the top catches from Week 12 of the 2025 NFL season.
video Top touchdowns | Week 12 Watch the top touchdowns from Week 12 of the 2025 NFL season.
video Top plays | Week 12 Watch the top plays from Week 12 of the 2025 NFL season.
video Top defensive plays | Week 12 Watch the top defensive plays from Week 12 of the 2025 NFL season.
video Top runs | Week 12 Watch the top runs from Week 12 of the 2025 NFL season.
video Panthers vs. 49ers highlights | Week 12 Highlights from the Week 12 matchup between the Carolina Panthers and the San Francisco 49ers during the 2025 NFL season.
video Christian McCaffrey's best plays from 142-yard game vs. Panthers | Week 12 Watch the best plays from San Francisco 49ers running back Christian McCaffery's 142-yard game against the Carolina Panthers in Week 12 of the 2025 NFL season.
video Ji'Ayir Brown snags his second INT of night on Bryce Young Carolina Panthers quarterback Bryce Young's pass to wide receiver Tetairoa McMillan is intercepted by San Francisco 49ers safety Ji'Ayir Brown for the second time tonight.
video Bryce Young zips RPO strike to Coker for 18 yards Carolina Panthers quarterback Bryce Young executes the RPO to perfection as he hits wide receiver Jalen Coker over the middle for a 18-yard gain into San Francisco 49ers territory.
video Matt Gay's 29-yard FG extends 49ers lead to 20-9 San Francisco 49ers kicker Matt Gay connects on a 29-yard field goal to extend the 49ers lead over the Carolina Panthers to 20-9.
video Purdy's play-action pass goes to Kittle for a 19-yard catch and run San Francisco 49ers quarterback Brock Purdy's play-action pass finds the wide open tight end George Kittle for a 19-yard catch and run against the Carolina Panthers.
video Christian McCaffrey explodes upfield for 17-yard run into Panthers territory San Francisco 49ers running back Christian McCaffrey bursts upfield for a 17-yard run into Carolina Panthers territory.
video Bryce Young drops 29-yard TD pass in the bucket to Tetairoa McMillan Carolina Panthers quarterback Bryce Young drops 29-yard touchdown dime to wide receiver Tetairoa McMillan to trim the San Francisco 49ers lead to 17-9.
video Chuba Hubbard shows off nifty juke moves on 14-yard catch and run Carolina Panthers quarterback Bryce Young hits running back Chuba Hubbard out of the backfield for a 14-yard catch and run after an electrifying juke move on a San Francisco 49ers defender.
video Christian McCaffrey's TD run marks the first time he's ever scored against Panthers San Francisco 49ers running back Christian McCaffrey takes the toss and bursts into the end zone for a 12-yard touchdown run against his former team.
video 3rd and Jauan! Jennings makes multiple defenders miss on 10-yard catch and run San Francisco 49ers quarterbacks hits wide receiver Jauan Jennings for a 10-yard catch and run on third down into the red zone.
video Rico Dowdle's spinning rush yields 17-yard pickup early in second half Carolina Panthers running back Rico Dowdle makes multiple San Francisco 49ers defenders miss on an incredible spin move that results in a 17-yard run.
video Matt Gay converts his first FG as a 49er San Francisco 49ers kicker Matt Gay connects on a 47-yard field goal to extend the 49ers lead to 10-3 over the Carolina Panthers.
video Purdy rips 25-yard strike to George Kittle San Francisco 49ers quarterback Brock Purdy connects with tight end George Kittle over the middle for a 25-yard gain into Carolina Panthers territory.
video Ryan Fitzgerald converts on 25-yard FG to trim 49ers lead to 7-3 Carolina Panthers kicker Ryan Fitzgerald connects on a 25-yard field goal to trim the San Francisco 49ers lead to 7-3.
video Jaycee Horn undercuts Brock Purdy's pass for second INT of night Carolina Panthers cornerback Jaycee Horn jumps the route and intercepts San Francisco 49ers quarterback Brock Purdy for the second time tonight.
video McCaffrey's fumble is somehow recovered by 49ers after Carolina fails to jump on ball San Francisco 49ers running Christian McCaffrey puts the ball on the ground but offensive tackle Colton McKivitz is somehow able to recover the fumble after multiple Carolina Panthers defenders are unable to recover it.