Mohamed Salah is on the bench again as Liverpool host Sunderland in an 8.15pm kickoff, with Arne Slot making only one change to his winning side from last time out.
After a rare win against West Ham on Sunday, the Premier League champions will look to follow it up at home to surprise package Sunderland.
Alisson will aim to make it back-to-back clean sheets behind a back four of Joe Gomez, Ibrahima Konate, Virgil van Dijk and Andy Robertson.
The midfield of Ryan Gravenberch, Alexis Mac Allister and the more advanced Florian Wirtz is retained, with Dominik Szoboszlai again on the right flank.
That comes with Salah left on the bench for a second game running as Cody Gakpo and Alexander Isak are rewarded for their goals at West Ham.
Joining Salah among the substitutes are the likes of Federico Chiesa, Curtis Jones and Milos Kerkez.
Liverpool: Alisson; Gomez, Konate, Van Dijk, Robertson; Gravenberch, Mac Allister; Szoboszlai, Wirtz, Gakpo; Isak
Substitutes: Mamardashvili, Endo, Kerkez, Salah, Chiesa, Jones, Ekitike, Nyoni, Ngumoha