Romeo Lavia, Liam Delap and Estevao
The Brazilian has now missed two games - a win at Cardiff and comeback draw at Newcastle - with a muscle issue, and Enzo Maresca hopes to have the teenager again available.
Estevao
Estevao has been sidelined with a "small muscle problem", according to manager Enzo Maresca.
The teenage star missed Tuesday’s 3-1 Carabao Cup quarter-final win against Cardiff, and his manager has confirmed he will also sit out the weekend trip to face Newcastle in the Premier League.
Standard Sport understands that Estevao faces a race to be fit for Chelsea’s first match after Christmas, when they host Aston Villa at Stamford Bridge on December 27.
Maresca said after the game at Cardiff: "He had a small problem. It was a muscle problem.
"He won’t be available for Newcastle and we will see for the next one."
Liam Delap
The striker is set for another extended spell on the sidelines this season, after suffering a shoulder injury against Bournemouth earlier in December.
Maresca makes Chelsea experience admission after comeback at Newcastle
Maresca set for second touchline ban as tempers boil over in Chelsea draw
Three things we learned from Chelsea draw as Maresca team talk works wonders
The new face of whisky investment
Delap had to be substituted 31 minutes into the 0-0 draw after Cherries defender Marcos Senesi landed awkwardly on him.
Chelsea are hopeful that Delap will have recovered inside four weeks, with the injury not as bad as first feared.
Asked for an updated return timeline on Friday, Maresca said: "We don't know yet [how long he will be out for].
“It can be still two, three, four weeks. We don't know exactly how many days he needs."
Dario Essugo
Dario Essugo is not expected to return before the end of the year.
The summer signing’s start was hampered by a thigh problem suffered in September, and then a return to training in November was cut short in which was thought to be a setback.
But Maresca has last week confirmed that Essugo has picked up a separate issue.
Asked for an updated timeline for his return, Maresca said: “I don’t know. I don’t have information. I know that he’s better.
“It’s not the same injury that he had in the past. It’s something small and it will be a short time.”
Romeo Lavia
“It's a muscle problem,” Maresca said earlier in December. “We don't know yet when he can be back.”
Pushed on whether Lavia is expected to be a short-term or long-term absentee, Maresca replied: “We don't know.”
Injury issues have restricted Lavia to just 29 appearances since his £53million move from Southampton in the summer of 2023.
Potential return date: Unknown
Levi Colwill
Levi Colwill will miss most of the season with an anterior cruciate ligament (ACL) injury.
A devastating injury in a World Cup year, the defender suffered the blow shortly after Chelsea returned for pre-season training at Cobham in August, days after winning the Club World Cup.
Colwill underwent surgery soon after and is expected to be sidelined for much of the campaign.