Liverpool's unbeaten run went up in smoke as Amine Adli scored a stoppage-time winner for Bournemouth in a dramatic 3-2 victory.
Arne Slot's team were unbeaten across 13 games in all competitions - a run slightly skewed by four straight draws in the Premier League - but fell to a last-gasp Adli strike having staged a fightback from 2-0 down.
Some haphazard defending from Virgil van Dijk gifted Evanilson the opener before Alex Jimenez doubled the lead with Liverpool dallying about replacing the injured Joe Gomez leaving them with just 10 men on the pitch when the goal went in.
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Bournemouth vs Liverpool
Jamie Redknapp criticised the time Liverpool took to replace the injured Joe Gomez as Bournemouth doubled their lead
Van Dijk headed Slot's team to within one goal, partially atoning for his earlier errors by turning home a Dominik Szoboszlai corner with the top of his back.
Andy Robertson, who has been linked with a move this month, replaced Milos Kerkez for a second half which mostly took place in Bournemouth territory.
Yet the reigning champions remained largely toothless in attack until Szoboszlai hammered home a free-kick with 10 minutes remaining as Liverpool's unbeaten run looked set to continue.
However, Andoni Iraola's side, who had won just once in their last 13 matches, were brave and bold in the closing stages and their gamble to throw men forward paid off when Adli netted a scrappy winner in the 95th minute.
Liverpool remain fourth after the defeat - 14 points adrift of leaders Arsenal - and could slip out of the Champions League places when Manchester United and Chelsea play on Sunday, while Bournemouth climb to 13th, 10 points clear of the relegation zone.
The Reds have now lost seven Premier League games this season and the future of boss Slot will be in the spotlight once again.
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