Big week: Gary Neville
Arsenal Football Newsletter
The Gunners restored their five-point lead at the top of the Premier League on Sunday with a hard-fought win over Chelsea, in which set-piece prowess and controversial refereeing decisions were again at the forefront.
Arsenal are back in Premier League action on Wednesday, at Brighton, before a FA Cup tie with Mansfield and a Champions League last-16 first-leg clash at Bayer Leverkusen. March will send with the Carabao Cup final against Manchester City at Wembley.
Arteta's side are favourites to win all four competitions as they look to become the first team in English football history to win an unprecedented quadruple.
And Neville believes the decisions Arteta makes this week will prove pivotal for the remainder of the season.
"You can't throw away a Champions League, you can't throw away a Carabao Cup final, so how Mikel Arteta rotates, how he uses his squad, how he stays clear of injuries is going to important," Neville told Sky Sports.
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"Arsenal have to in some ways take a calculated risk in the FA Cup. That's not to disrespect it but you have to look it at and trust your second XI right up to the semi-final. The Carabao Cup final is a one-off game, you have to play your best team. The Champions League you have to play your best team, and obviously in the Premier League.
"But the FA Cup does give Mikel Arteta a chance to take a risk. That might be the competition they falter in - they've got Mansfield in the fifth round so they'll probably get across the line there, but as it goes through that'll be the one which might fall by the wayside."