Guardiola’s side have already booked a place in the Carabao Cup final, against Arsenal, and remain in the Premier League title race which means an unprecedented quadruple is achievable.
Despite no let-up in the fixture schedule, the Man City boss has stressed the importance of the FA Cup, thus hinting at going strong against the Magpies.
“How many finals did we play in the last years? How many semi-finals? A lot, that means always FA Cup is so important,” Guardiola told reporters on Friday.
“We are going to travel to Newcastle to win and get to the next round.
“That’s definitely 100%.”
Sticking to his policy of rotating goalkeepers for the cup competitions, Guardiola is set to hand James Trafford a start as Gianluigi Donnarumma is rested.
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Trafford impressed in both Carabao Cup semi-final ties against Newcastle, keeping a clean sheet in the first-leg at St. James’ Park as City ran out 2-0 winners.
Antoine Semenyo was on the scoresheet that night and should keep his place, with Omar Marmoush coming into the side given his impressive record against the Magpies.
Erling Haaland is fit to lead the line after shaking off a minor knock that kept him out of the win over Leeds and Nico O’Reilly should be available after sitting out the 2-2 draw with Nottingham Forest.
There could be a change in central defence with Abdukodir Khusanov getting the nod over Ruben Dias to help combat Newcastle’s pacy forward line.
Predicted Man City XI: Trafford; Nunes, Khusanov, Guehi, Ait-Nouri; Rodri; Semenyo, Bernardo, O’Reilly; Haaland, Marmoush.
Injured: Kovacic, Gvardiol
Doubts: O’Reilly, Alleyne
How to watch: TNT Sports
Venue: St. James’ Park