It's Eddie Howe vs Pep Guardiola for the fifth time this season as the Magpies and the Citizens meet on Tyneside.
A place in the FA Cup quarter-final awaits the winner of this weekend's tie, with Newcastle hopeful of booking their spot in the last eight for the first time since the 2023-24 season.
[Howe delivered a team news update on Friday morning](https://www.newcastleunited.com/en/news/eddie-howes-team-news-update-woltemade-livramento-and-miley-latest), with Nick Woltemade passed fit after a bout of illness in midweek.
Before the action gets underway, you can test your FA Cup and United knowledge with our pre-match quiz.
See if you can score 100%!