With Yamal on the bench, Roony Bardghji and Dani Olmo have been drafted into the attacking unit to support Robert Lewandowski. The lineup also features a full debut for youngster Xavi Espart at right-back, as Eric Garcia is only on the bench after missing the first leg at Newcastle due to an overload.
The atmosphere is expected to be electric, aided by the opening of additional seating sections in the stadium which will extend the capacity to 62,000. Flick added: "I'm waiting to see the fans today. Against Atletico Madrid we experienced a great atmosphere and I hope that today too. It is very important to have that support."