Arsenal return from the international break and go straight into cup action as they travel to face Southampton in the quarter-finals of the FA Cup this evening.
The Gunners saw their hopes of winning an historic quadruple ended in their last game as they lost 2-0 to Manchester City in the Carabao Cup final. A poor performance saw Mikel Arteta's side fall to a Nico O'Reilly brace.
Saints defeated Oxford United 2-0 before the break to continue their 14-game unbeaten run that stretches back to mid-January. Their victory over the U's kept them within a shout of reaching the Championship promotion play-offs.
Prevented from immediately bouncing back by the international break, Arteta will be hoping his side can show that they are eager to win trophies with a victory at St Mary's. With an FA Cup semi-final on the line, this is certainly a big game for both teams.
Here's our preview of Arsenal's trip to Southampton.
Southampton vs Arsenal: Preview, Prediction & Lineups
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A potential start? | Visionhaus/GettyImages
### What time does Southampton vs Arsenal kick off?
Southampton vs Arsenal kicks off on Saturday 4 April at 20:00 BST.
* **When is kick off?** Saturday 4 April, 2026
* **What time is kick off?** 20:00 BST
* **Where is it played?** St Mary's Stadium
* **Referee:** Sam Barrott
### Southampton vs Arsenal head-to-head record
**Club**
**Wins**
**Draws**
**Losses**
Southampton
23
30
55
Arsenal
55
30
23
### Southampton vs Arsenal last five meetings
**Date**
**Result**
**Competition**
25 May 2025
Southampton 1-2 Arsenal
Premier League
5 October 2024
Arsenal 3-1 Southampton
Premier League
21 April 2023
Arsenal 3-3 Southampton
Premier League
23 October 2022
Southampton 1-1 Arsenal
Premier League
16 April 2022
Southampton 1-0 Arsenal
Premier League
### How to watch Southampton vs Arsenal
**Country**
**TV channel/live stream**
United Kingdom
BBC, TNT Sports
Australia
Stan Sport
Canada
Sportsnet World, Sportsnet Plus, Sportsnet 360
United States
ESPN Select, fuboTV, ESPN App
### Southampton vs Arsenal score prediction
Despite facing a side from the league below, Arsenal will have their work cut out for them tonight at St Mary's. Not only have Southampton proven to be a bogey team for the Gunners in the past, their recent unbeaten form bodes well for them.
However, the Gunners should have enough to get over the line on the South Coast and secure their spot in the semi-finals of the FA Cup. It won't be easy for them and they will have to work for it, but Arsenal will progress to the last four tonight.
### Prediction: Southampton 1-2 Arsenal