Arsenal have lost out on another trophy after a shock 2-1 defeat away to Southampton in the FA Cup quarter-finals.
Shea Charles came off the bench to score the decisive goal with only five minutes to play at St Mary's on Saturday night.
Shea Charles celebrates for Southampton.
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Charles has sent Southampton into the FA Cup semi-finalsCredit: Getty
Arsenal looked to be heading for extra time when Viktor Gyokeres levelled after Ross Stewart opened the scoring for Southampton.
But the Gunners, who lost to Manchester City in the Carabao Cup final less than two weeks ago, are now out of the FA Cup.
It's a significant moment in the season run-in, and comes just weeks after Arsenal were eyeing up a historic quadruple.
They remain top of the Premier League and will play in the quarter-finals of the Champions League.
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However, the pressure will really begin to kick in when they navigate the final weeks of the campaign.
"Southampton have dumped out the Premier League leaders," said Alex Crook on talkSPORT. "The treble dream is over."
Former Gunner Perry Groves added: "Southampton thoroughly deserved it, both goals they scored were top quality."
"(Taylor) Harwood-Bellis was perfect, every Southampton player to a man did their job to perfection," he also said.
Arsenal were dealt a blow before the full-time whistle as Gabriel was substituted with an injury.
He was seen sitting on the bench with ice on his leg, with Mikel Arteta and co. now set for an anxious wait to see how bad the knock is.
Arsenal after conceding to Southampton.
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Arsenal have lost out on two pieces of silverware in two weeksCredit: Getty
Graphic of Arsenal losing in competitions.
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The Gunners have gone from potentially winning four trophies, to only two
Is this when it comes crashing down?
Arsenal have been the most impressive side in the Premier League this season and looked strong when competing on all fronts.
However, as seen in recent years, the final weeks of the season have been too much to handle - and history could be repeating itself.
Southampton, who will play in the FA Cup semi-finals for the first time since 2021, were the deserved winners on the night.
Arsenal on the other hand were void of any real quality, and have lost back-to-back games for the first time all season.
They return to action on Tuesday night against Sporting for their Champions League quarter-final first leg.
Some of the players' heads may well have dropped after defeat at Southampton, with Groves concerned about their mentality.
Arsenal after losing in the FA Cup against Southampton.
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Another week, another cup defeat for ArsenalCredit: Getty
"It could have a huge impact, we won't know until the Sporting game," he said. "The treble team is done and dusted, now they're going for the double.
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"This had got to hurt…they looked disjointed
"It wasn't due to lack of effort, but they couldn't match the intensity of the Southampton players."