From back to front in what we expect will be a 4-2-3-1 formation, it's Senne Lammens in goal, behind a defence which could line up in several ways, with the incoming Heaven our only recognised centre-back. One of Dalot, Noussair Mazraoui and Luke Shaw appear primed to partner the 19-year-old in the middle.
Further up the pitch, Mainoo is back from the training injury that saw him miss the Leeds match, to slot back into the midfield alongside Casemiro.
The Brazilian was on the scoresheet alongside captain Bruno Fernandes in September's reverse fixture, a 2-1 win for United, and our Portuguese skipper is likely to continue behind striker Benjamin Sesko, with Mbeumo and Matheus Cunha on the wings.
Along with Ugarte and Amad, United's bench includes former Chelsea man Mason Mount and Academy midfielder Jim Thwaites, who played the full 120 minutes of our Under-18s' triumph in the FA Youth Cup semi-final at Old Trafford on Friday.