It will be a whole lot easier for Iraola to get Isak firing if he can figure out how to unlock Florian Wirtz's enormous potential.
For a split-second midway through the 2025-26 campaign, it actually felt like everything was going to click into place for Liverpool. Isak confidently converting a lovely little through-ball from Wirtz in the 2-1 win at Tottenham on December 20 provided the long-suffering supporters with a glimpse of a brighter future.
It proved nothing more than a glimpse, though, because Isak was left with a broken leg after being wiped out by Micky van de Ven immediately after scoring and wouldn't feature again in the Premier League for a further four months.
Of course, Wirtz continued to show flashes of his undoubted genius - particularly while working in tandem with Hugo Ekitike before the Frenchman's devastating, year-ending injury. However, while fate conspired against the Germany international on more than a couple of occasions, there's no denying that Wirtz went missing far too many times, and particularly in big games.
The hope is, though, that the shift in style we're now set to see under Iraola will benefit the £100m signing from Bayer Leverkusen, who should take up the No.10 role in the coach's preferred 4-2-3-1 formation.
Wirtz, though, is also under pressure to prove that he can cope with the intensity and physicality of the Premier League - and thus dismiss claims that Liverpool would be better served by deploying the hard-running Dominik Szoboszlai in front of Ryan Gravenberch and Alexis Mac Allister.
Getting the make-up of the midfield right really is of the utmost importance to Iraola, because the Reds were repeatedly overrun last season, with Gravenberch providing more attacking threat but less defensive cover, and Mac Allister appearing utterly exhausted.
Do not be surprised, then, if Iraola asks his new employers for the specialist No.6 Liverpool have lacked for so long to lighten the load on Gravenberch, restore some badly needed balance to the side and allow Wirtz to go and do what he does best: create.