Coventry's first game back in the Premier League for 25 years sees them travel to champions Arsenal.
All 380 games for the 2026/27 have been released and also sees newly-promoted Hull hosting Michael Carrick's Manchester United.
Mikel Arteta with the Premier League trophy
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Mikel Arteta's champions face Coventry on the first day of the new seasonCredit: Getty
Liverpool, under new manager Andoni Iraola, travel to Newcastle with a fit again Alexander Isak, who swapped the north east for the north west in a £125m transfer.
Tottenham travel to Brentford and feel they have the right manager in charge in Roberto De Zerbi who guided them to safety on the final day of the 2025/26 season.
Ipswich are at home against Sunderland but fans are still waiting to see who will be in charge following Kieran McKenna's exit.
When does the season begin?
Arsenal, winners last season, begin on Friday 21 August, with the final day taking place on 5 June, a week before the Champions League final.
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The Premier League addressed the packed festive schedule and over Christmas and New Year period, no two match rounds will take place within 60 hours of each other.
Opening weekend live on talkSPORT
talkSPORT will be across all of the opening weekend's action with two games to be broadcast live on the station.
Our dedicated team will be at the Emirates as Arsenal kick off their title defence against Coventry.
Likewise, fans can catch all of the action from the MKM Stadium when newly-promoted Hull host Manchester United at Saturday lunchtime.
Boxing Day is back!
Fans will be delighted to know that the traditional Boxing Day schedule will return to its usual slot on 26 December.
Just one Premier League fixture took place on Boxing Day last season sparking major backlash from fans.
Opening day fixtures
Friday 21 AugustArsenal v Coventry City: 8am
Saturday 22 AugustHull vs Man United: 12:30
Everton vs Crystal Palace: 3pm
Ipswich vs Sunderland: 3pm
Nottingham Forest v Leeds United: 3pm
Brentford vs Tottenham: 5:30pm
Sunday 23 AugustBrighton vs Aston Villa: 2pm
Man City vs Bournemouth: 2pm
Newcastle vs Liverpool: 4:30pm
Monday 24 AugustFulham vs Chelsea: 8pm
Coventry City manager Frank Lampard celebrates with the trophy Coventry City v Wrexham
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Lampard's Coventry go to Arsenal on the opening day and he host former club Chelsea in DecemberCredit: Shutterstock Editorial
Sergej Jakirovic celebrates with the Championship play-off trophy
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Hull City celebrate their return to the top tier by hosting Man United on the first Saturday game of the season, which is live on talkSPORTCredit: Getty
But there will be no such controversy this time around with multiple games expected to be televised on the day, pending broadcasting picks.
Arsenal face a festive trip to the the scene of their title celebrations when they face Crystal Palace at Selhurst Park.
Newcastle United host Manchester City, Nottingham Forest travel to Old Trafford to take on Manchester United and Hull entertain Liverpool.
Elsewhere, Tottenham take on Bournemouth, Frank Lampard faces an emotional reunion with former club Chelsea at the CBS Arena and Aston Villa host Leeds.
The final day of the season takes place at the later that usual date of May 30.
Those matches see Arsenal take on Brighton while Man City travel to Sunderland and Liverpool boss Iraola welcomes former club Bournemouth to Anfield.
Every club's fixtures for the 2026/27 season are on talkSPORT's dedicated page.