Well, it is a new week and a new chance to improve.
The improvement doesn’t necessarily have to be wins, although that would be really nice, but showing that this team has a little life and can compete in the division.
Nothing else matters right now outside of what can you do against your division opponents? The Cardinals can afford to be 0-2 early, but they cannot afford to be 0-2 with a -45 or more point differential in two games inside the division, because that makes everyone feel like there has been no improvement.
Barry is back! and will have a TV Maps for us in a bit, showing where the game is available and more, but real quick, here is everything you need to know about this afternoons game.
**Date:** Sunday, September 27, 2026
**Time:** 1:05 p.m. AT
**Location:** Levi’s Stadium — Santa Clara, CA
**National TV:** Fox (Channel 10 locally)
**National online streaming**: FoxSports
**TV announcers:** Kevin Kugler (play-by-play) Daryl Johnston (analyst) Allison Williams (sideline)
**Radio:** Arizona Sports 98.7 FM
**Radio announcers:** J.P. Shadrick (play-by-play), A.Q. Shipley (analyst), Dani Sureck (sideline)
**Spanish Radio:** Latino Mix 100.3 FM KQMR
**Spanish Radio announcers:** Jesus Quinonez (play-by-play) and Irving Villanueva (analyst)
**Betting line: Cardinals +8.5 per [FanDuel Sportsbook](https://sportsbook.fanduel.com/football/nfl/arizona-cardinals-@-san-francisco-49ers-36076217)**
See More:
* [Arizona Cardinals Game Information](/arizona-cardinals-game-information)