Sep 20, 2026; Santa Clara, California, USA; San Francisco 49ers running back Christian McCaffrey (23) celebrates with quarterback Brock Purdy (13) after scoring a touchdown in the first quarter against the Miami Dolphins at Levi's Stadium. Mandatory Credit: Cary Edmondson-Imagn Images
The Week 6 NFL schedule wraps up with a Monday Night Football matchup between the
Washington Commanders and San Francisco 49ers.
San Francisco enters at 5-0 and averages 30.8 points per game, while Washington comes off a 27-27 overtime tie with the Giants.
With several injuries affecting Washington’s offense, some intriguing player props stand out.
MORE: NFL power rankings, updated entering Sunday Week 6
Christian McCaffrey and Kaelon Black provide value for San Francisco
NFL: San Francisco 49ers at Los Angeles Chargers
Aug 20, 2026; Inglewood, California, USA; San Francisco 49ers running back Kaelon Black (26) runs with the ball during the first quarter against the Los Angeles Chargers at SoFi Stadium. Mandatory Credit: Kiyoshi Mio-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)
Kaelon Black OVER 14.5 rushing yards
Black is an intriguing lower-number rushing prop because his workload could increase if San Francisco decides to establish the run. Christian McCaffrey will remain the centerpiece, but the 49ers have shown a willingness to rotate their backs.
Black could see additional opportunities if San Francisco builds a lead, particularly in the second half. Black could receive 10-15 opportunities if the 49ers commit to a run-heavy approach.
At just 14.5 rushing yards, Black doesn’t need a massive workload to cash this over.
Christian McCaffrey OVER 3.5 receptions
McCaffrey’s receiving workload makes this one of the more appealing props on the board. The 49ers have plenty of offensive weapons, but McCaffrey remains one of Brock Purdy’s most reliable outlets, particularly when defenses create pressure or take away downfield options.
San Francisco is also dealing with injuries at wide receiver. Deebo Samuel is out with a hamstring injury, while Mike Evans is dealing with rib and Achilles issues. That could create even more opportunities for McCaffrey to be involved as a receiver.
Terry McLaurin and Rachaad White could benefit from Washington’s situation
NFL: Seattle Seahawks at Washington Commanders
Sep 27, 2026; Landover, Maryland, USA; Washington Commanders wide receiver Terry McLaurin (17) reacts after making a touchdown catch against the Seattle Seahawks in the second half at Northwest Stadium. Mandatory Credit: Amber Searls-Imagn Images Credit: IMAGN IMAGES via Reuters Connect (Reuters)
Terry McLaurin OVER 39.5 receiving yards
McLaurin is the Commanders’ most established downfield receiving threat, and the matchup could force Washington to throw. The Commanders are 1-3-1 while San Francisco is undefeated, creating a strong possibility that Jayden Daniels will have to keep throwing if Washington falls behind.
McLaurin has 203 receiving yards on 14 receptions this season, and he practiced Saturday after dealing with a hamstring issue. A 39.5-yard line is low enough that McLaurin could clear it with only a handful of meaningful catches.
Rachaad White OVER 2.5 receptions
This might be the most interesting Washington prop following the news that Jacory Croskey-Merritt is out with a groin injury. Croskey-Merritt leads Washington with 239 rushing yards, so his absence could significantly alter the Commanders’ backfield usage.
White is expected to operate as Washington’s lead back, and he should see increased passing-game involvement. White had an 8% target share entering the matchup, while San Francisco had allowed the most receptions to running backs in the NFL.
If Washington is forced into catch-up mode, White could see several checkdowns from Daniels. That makes OVER 2.5 receptions an especially appealing number.
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