The final game of Week 6 will be a _Monday Night Football_ matchup featuring the Washington Commanders (1-3-1) on the road against the San Francisco 49ers (5-0).
The 49ers lead the all-time series between these teams, 20-11-1, and have won three of their four most-recent meetings. They last faced off back in 2023, when the 49ers had an easy day on the East Coast against the Commanders, winning 27-10.
Here’s everything you need to know about tonight’s game.
**Date**: Monday, October 18, 2026
**Location**: Levi’s Superdome | Santa Clara, CA
**Announcers:** Joe Buck, Troy Aiman, Lisa Salters (field reporter) and Laura Rutledge (field reporter)
**Washington Commanders:** +7.5 (+330)
**San Francisco 49ers:** -7.5 (-420)
_Open thread: Discuss Monday night’s game in the comments below._
See More:
* [Game day threads](/game-day-threads)
* [Philadelphia Eagles discussion](/philadelphia-eagles-discussion)