The 2025 NFL Draft class is starting to take shape, and that means we’re getting a clearer picture of some of the top prospects and the position groups with the most depth.
The running back, tight end and offensive tackle positions seem to be the deepest and strongest on the offensive side of the ball. On defense, the edge defender group is as deep as we’ve seen in several years, dominating the projected top 50. There are also more impact defensive backs this year than a year ago, with plenty of options on all three days of the draft, specifically on Days 2 and 3.
Here are PFF's top interior defensive linemen in the 2025 NFL Draft, along with some initial scouting notes courtesy of lead draft analyst Trevor Sikkema.
For the full ranking of draft prospects, along with their three-year player grades and position rankings, click here.
DI1. Mason Graham, Michigan
Big board rank: 4
Graham has shorter-than-ideal arms for an NFL interior defensive lineman, but outside of that, there is a lot to love. He is fast, violent and relentless, and he can stop the run with great strength. He brings a high floor at all times and a high ceiling in flashes as a 3-technique defensive tackle for a 4-3 front.
DI2. Kenneth Grant, Michigan
Big board rank: 17
Grant brings a rare combination of quickness and size to the nose tackle position. He has the strength to dominate single blocks and hold up against doubles. When he’s in attack mode, he is an imposing player — I just wish we saw that aggressive mindset more consistently.
DI3. Derrick Harmon, Oregon
Big board rank: 22
Harmon has just one year of notable production, but that season showcased a player with a high football IQ, consistent competitiveness and NFL-level quickness. He can be an effective 3-technique defensive lineman for an even front.
DI4. Darius Alexander, Toledo
Big board rank: 23
Alexander was lightly recruited and was a late bloomer in college football (will be 25 in his rookie season), but his measurables and strength are NFL-caliber. He is a contributing NFL defensive lineman at worst due to his strength profile, with starting caliber impact potential in odd and even fronts.
DI5. Walter Nolen, Ole Miss
Big board rank: 25
Nolen isn't the most polished interior defender, but he might be among the most physically gifted. If he continues to grow in his pre-snap plan and hand usage, he can be an impactful, versatile defensive tackle with a high floor due to his strength in run defense.