When asked if he expected any of his absentees to return against La Real, Ruben replied: "Maybe Ugarte, I don't know, we'll see."
In a separate interview, Amorim was a little stronger on the South American's fitness, saying: "I think Manu will return."
Meanwhile, Yoro will obviously be assessed when the squad gets back to Carrington to prepare for the European tie.
"Leny, he has something in his foot," he added. "I think. We'll see if he's available on Thursday."